Clin2
NCT06750952Possibly a fitNot yet recruiting

First-line treatment for advanced or recurrent thymic cancer

Relapsed or Metastatic Thymic CancerFirst-line Treatment

Treatments studied

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a combination of an immunotherapy drug (ivonescimab) plus chemotherapy as the first treatment for people with advanced or recurrent thymic cancer. The goal is to see how well this combination works and how safe it is.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
24 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are at least 18 years old.
  • You have thymic cancer that has spread (metastatic) or come back (recurrent) and cannot be removed with surgery.
  • You have not received any prior treatment for this cancer (this will be your first treatment).
  • You are generally able to take care of yourself (ECOG performance status 0-1) and expected to live at least 3 more months.
  • You have adequate organ function, including blood counts, kidney, liver, heart, and thyroid function.
  • You have not had immunotherapy (like PD-1/PD-L1 inhibitors) or anti-angiogenic drugs before.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06980077Recruiting· Phase 2
Ivonescimab for advanced thymic carcinoma

This trial tests a new drug called ivonescimab for thymic carcinoma that has come back or isn't responding to other treatments. It aims to see if this drug can shrink the cancer and help you feel better.

Davis, California
NCT06951646Recruiting· Phase 2
Personalized treatment for advanced lung cancer with long response to first-line therapy

This trial tests a combination of ivonescimab and docetaxel for people with advanced non-small cell lung cancer who have had a long response (11-15 months without the cancer getting worse) to first-line immunotherapy. The goal is to see if adjusting treatment based on ctDNA-MRD levels can improve outcomes.

Changsha
NCT07009925Not yet recruiting· Phase 2
New drug combo for first-line advanced squamous lung cancer

This trial tests a new combination of three medicines (two chemotherapies and an immunotherapy) for people with a certain type of advanced lung cancer called squamous non-small cell lung cancer. The goal is to see if this combo can help shrink or control the cancer better than current treatments.

NCT06846346Recruiting· Phase 2
Testing Ivonescimab with Chemo for Advanced Stomach Cancer

This trial tests a new immunotherapy drug called ivonescimab given together with standard chemotherapy for advanced stomach cancer. It may help your immune system fight the cancer more effectively.

Lyon
NCT07094685Recruiting· Phase 2
Ivonescimab before surgery for head and neck cancer

This study tests a new immunotherapy drug called ivonescimab given before surgery for people with advanced head and neck cancer. The goal is to see if it helps shrink the tumor and improve outcomes.

Ann Arbor, Michigan
NCT07696832Recruiting
Ivonescimab as first treatment for advanced lung cancer

This trial studies ivonescimab alone as a first treatment for people with advanced non-small cell lung cancer (NSCLC) that tests positive for PD-L1 and doesn't have certain gene changes. The goal is to see if it works and is safe in everyday medical practice.

Guangzhou, Guangdong

Hear when a new First-line Treatment trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.