Clin2
NCT06755697Possibly a fitRecruiting

Comparing injection methods for knee osteoarthritis

Knee OsteoarthritisGlucoseProlotherapyMRIPhysical TherapyRehabilitation

Part of Bones, joints & muscles clinical trials.

This trial compares two ways to give dextrose injections for knee osteoarthritis: one into the joint space and one guided by MRI into the tissues around the knee. It aims to see which approach works better for pain and function.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
60 people
Ages
45 years to 80 years
Study type
Interventional

Who can take part

  • You are between 45 and 80 years old.
  • You have at least three signs of knee osteoarthritis, like age over 50, morning stiffness less than 30 minutes, a cracking knee, tender bone, bony swelling, or no warmth to the touch.
  • Your knee X-ray shows moderate arthritis (grade 2 or 3).
  • You are willing to receive prolotherapy (dextrose injections into or around the knee).
  • You have not had knee surgery, are not planning knee replacement, and have not had a knee injection in the last 3 months. You are not taking blood thinners and do not have a BMI over 35.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07243392Not yet recruiting
Steroid, dextrose, and platelet-rich plasma injections for knee osteoarthritis

This trial compares three common injection treatments for knee osteoarthritis to see which one works best for pain relief. It tests a steroid, a dextrose solution, and platelet-rich plasma (a treatment made from your own blood).

Lahore, Punjab Province
NCT07245121Recruiting
Sugar water injections for chronic knee arthritis pain

This trial tests whether injecting a sugar-water solution around the nerves of the knee can reduce chronic pain from osteoarthritis. It is for people with long-term knee pain, stiffness, and cracking who have not had recent knee treatments or surgery.

Athens, Attica
NCT07381621Recruiting
Comparing sugar water vs. numbing shots for knee arthritis

This study compares two different types of knee injections for people with knee osteoarthritis. One injection uses a simple sugar solution (dextrose), and the other uses a standard numbing medication (local anesthetic). The goal is to see which works better for reducing pain and improving knee function.

Ankara, Altindag
NCT06797960Not yet recruiting· Early Phase 1
Comparing two knee injections for osteoarthritis pain

This study compares two treatments for knee pain from osteoarthritis: a natural substance made from your blood (platelet-rich fibrin) and a joint lubricant (hyaluronic acid). Both are injected into the knee to see which gives better pain relief.

NCT07016672Recruiting
PRP vs. hyaluronic acid for advanced knee arthritis

This study compares two treatments—platelet-rich plasma (PRP) and hyaluronic acid (a lubricating injection)—for people with severe knee arthritis seen on MRI. The goal is to see which better reduces pain.

Toulon, Var
NCT03734900Recruiting· Phase 4
Comparing two knee injection treatments for osteoarthritis

This study compares two knee injection treatments for knee osteoarthritis. It aims to see which one works better for reducing pain and improving function, so you might experience less knee pain and better mobility.

Taipei

Hear when a new Knee Osteoarthritis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.