Which knee arthritis injection works best?
Part of Bones, joints & muscles, Pain clinical trials.
This study compares three different injection treatments for knee osteoarthritis: a steroid (cortisone), dextrose prolotherapy (sugar water), and platelet-rich plasma (using your own blood). The goal is to see which works best for long-term pain relief and joint function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 80 years old.
- You have been diagnosed with knee osteoarthritis (wear-and-tear arthritis) that is moderate to severe.
- You have had steady knee pain for at least the last 6 months.
- You have not had any knee surgery recently.
- You do not have an inflammatory joint disease like rheumatoid arthritis.
- You do not have an active infection, uncontrolled diabetes, and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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