Turmeric vs. steroid injections for mouth tightness
Treatments studied
Part of Mouth & dental clinical trials.
This trial compares a turmeric compound (curcumin) to steroid injections for treating oral submucous fibrosis, a condition that makes it hard to open your mouth. It aims to find which treatment works better with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with oral submucous fibrosis (mouth tightening).
- You are male or female.
- You are able to stop chewing gutkha, tobacco, or betel nut.
- You do not have uncontrolled diabetes.
- You do not have chronic kidney disease.
- You are not pregnant, do not have untreated cancer, and are not taking immune-suppressing drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether switching between two treatments—triamcinolone (a steroid) and platelet-rich plasma (from your own blood)—can help people with oral submucous fibrosis. The study aims to improve mouth opening and reduce burning pain.
This study tests if a special laser therapy (photobiomodulation) helps people with oral submucous fibrosis open their mouths wider. It's for people who haven't had other treatments for this condition in the last three months.
This trial tests two methods of injecting triamcinolone (a steroid) into the narrowed part of the throat (subglottic stenosis) to see which works better: one guided by a camera during an endoscopy, the other guided by ultrasound. It may help people who have trouble breathing or a hoarse voice due to this condition.
This trial tests whether injections of donor stem cells can reduce mouth tightness and improve daily function in people with systemic sclerosis (scleroderma). It focuses on those with significant mouth involvement and limited mouth opening.
This trial tests a new gel made from curcumin (a natural substance found in turmeric) combined with a standard deep cleaning treatment for Stage III gum disease. The goal is to see if the gel helps reduce gum inflammation and improve healing.
This trial tests if combining a deep dental cleaning (periodontal treatment) with a corticosteroid medicine can help heal painful mouth sores from erosive oral lichen planus. It is for people who also have advanced gum disease.
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