Alternating treatments for oral mouth fibrosis
Treatments studied
Part of Brain & nervous system, Mouth & dental clinical trials.
This trial tests whether switching between two treatments—triamcinolone (a steroid) and platelet-rich plasma (from your own blood)—can help people with oral submucous fibrosis. The study aims to improve mouth opening and reduce burning pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have been diagnosed with oral submucous fibrosis stage 2, 3, or 4.
- You must be between 18 and 65 years old.
- Your mouth opening must be 30 millimeters or less.
- You must have a persistent burning feeling in your mouth rated 3 or higher on a 0–10 pain scale.
- You must be able and willing to attend weekly therapy sessions.
- You must not have had certain treatments for this condition in the past 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if a special laser therapy (photobiomodulation) helps people with oral submucous fibrosis open their mouths wider. It's for people who haven't had other treatments for this condition in the last three months.
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This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.
This trial tests if combining a deep dental cleaning (periodontal treatment) with a corticosteroid medicine can help heal painful mouth sores from erosive oral lichen planus. It is for people who also have advanced gum disease.
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