De-intensified therapy for HPV-positive throat cancer
Part of Cancer clinical trials.
This trial tests a less intense treatment approach for people with HPV-positive oropharyngeal cancer. It uses surgery first, followed by fewer or lower doses of radiation and chemotherapy, aiming to reduce side effects while keeping treatment effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have HPV-positive oropharyngeal cancer (confirmed by a p16 test or other HPV test).
- Your cancer stage must be T1-T3, N0-N2b (older staging) or T1-T3, N0-N1 (newer staging).
- Your care team must plan to treat you with surgery first (transoral resection and neck dissection).
- You must be at least 18 years old.
- You must not have had radiation therapy to your head or neck before.
- You must not be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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