Spotlight on bone cancer: SBRT plus surgery
Part of Cancer clinical trials.
This trial tests if giving a high dose of focused radiation (SBRT) before surgery can improve outcomes for people with aggressive soft tissue sarcoma in an arm or leg. You may be able to avoid chemotherapy and still have a good result.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have a confirmed diagnosis of soft tissue sarcoma (a type of cancer in muscles, fat, or connective tissue).
- Your cancer must be a high-grade (fast-growing) type.
- You have not had any previous treatment for this cancer, such as surgery, chemotherapy, or other anti-cancer therapy.
- You are in good general health (ECOG score 0 or 1, meaning you can do all usual activities or only light work).
- You are willing to provide a tissue sample (biopsy) and blood samples before and after treatment.
- You cannot be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests combining anlotinib (a targeted therapy), doxorubicin (chemotherapy), and radiation given before surgery to shrink high-grade soft tissue sarcomas. The goal is to make the tumor easier to remove and improve outcomes.
This trial tests if a powerful type of radiation called carbon ion therapy, given before surgery, is safe and effective for treating soft tissue sarcoma. It may help shrink the tumor before it’s removed.
This trial tests a shorter course of radiation (just 5 days) before surgery for soft tissue sarcoma. The goal is to see if a brief, high-dose radiation schedule works as well as or better than the usual longer course—and may be more convenient for you.
This trial tests giving a shorter, lower-dose radiation treatment before surgery for a retroperitoneal (deep belly/back space) soft-tissue sarcoma. The goal is to shrink or control the tumor and make surgery more effective and safe.
This trial studies giving radiation before surgery to help control a soft-tissue sarcoma while keeping surgery as less extensive as possible. It may help shrink the tumor and improve what the surgeon can remove.
This trial tests a new type of radiation called spatially fractionated radiation therapy (SFRT) given before surgery for large soft tissue sarcomas in the arm, leg, or trunk. The goal is to see if it helps shrink the tumor and improve treatment outcomes.
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