Heart-lung machine left ventricle unloading study

This study monitors how much blood is reaching the brain in adults who need a specific type of life-support called VV-ECMO. The goal is to better understand brain blood flow and how monitoring may help manage care during ECMO.

This trial looks at using a specific heart-lung support machine (the EUROSETS ECMOLIFE system) for adults who need urgent “extra” circulation support. It may help clinicians understand how well the device works in serious situations like shock, cardiac arrest, or after heart surgery.

This study looks at using an external life-support machine after heart surgery. It may help patients who need temporary extra support while the heart and body recover.

This study examines how blood clotting cells (platelets) behave when patients are on a heart-lung support machine called ECMO. Researchers will take small blood samples to understand if the machine affects platelet function and how to manage blood thinning medication safely.

This study will look at whether “left ventricular unloading” (using a device like IABP or Impella) helps people who are in cardiogenic shock while on VA ECMO. It compares outcomes for people who get unloading versus those who stay on VA ECMO alone.

This trial tests a possible treatment to help the heart recover faster in people who need ECMO support for severe cardiogenic shock (when the heart can't pump enough blood). The treatment involves early use of a device to reduce pressure on the heart's main pumping chamber.