Optimizing antibiotic dosing in ICU patients with septic shock
Part of Infections clinical trials.
This trial checks if giving higher doses of beta-lactam antibiotics (a type of strong antibiotic) right from the start helps people in the ICU with septic shock. It aims to find the best dose to fight the infection quickly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- 18 years or older
- Getting intravenous beta-lactam antibiotics through a continuous drip
- Have a confirmed infection that started in the ICU
- In the ICU with septic shock (needing medicine to keep blood pressure up and having high lactic acid levels)
- Able to give informed consent within 72 hours of being admitted
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two ways of giving a strong antibiotic (meropenem) to ICU patients with pneumonia and sepsis. It aims to see if giving the drug continuously or in shorter intervals works better. This could help clear the infection faster and improve recovery.
This trial tests a computer tool to help doctors choose the right antibiotic for sepsis early on. It may help improve treatment by providing personalized recommendations based on your condition.
This trial tests a way to give the antibiotic cefepime to ICU patients. It aims to see if the dosing can be adjusted more precisely for each person.
This study tracks how doctors treat septic shock in the ICU to learn what works best. If you have septic shock, joining this study helps researchers understand which treatments are most effective, and you'll get the same care you would anyway.
This trial looks at how the immune system changes after septic shock in adults in the ICU. It may help doctors better predict or manage complications by studying blood markers a few days after starting treatment.
This trial tests a type of antibiotic called aminoglycosides to treat early sepsis (a serious infection). It is for adults in the hospital who are sick enough to need strong antibiotics but not in the worst stage of the illness.
Hear when a new Sepsis - to Reduce Mortality in the Intensive Care Unit trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.