Clin2
NCT06767358Likely a fitNot yet recruiting

Ketamine for sedation in the intensive care unit

Mechanical VentilationCritically Ill Intensive Care Unit Patients

Treatments studied

This study tests whether ketamine, a sedative and painkiller, works better than usual sedatives in ICU patients who need help breathing. If you qualify, taking part may help reduce the amount of other sedatives you need.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
54 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older and currently in the intensive care unit (ICU).
  • You are on a breathing machine and will likely need it for at least another day.
  • You have been on the breathing machine for less than 3 days.
  • You are receiving a continuous sedative (calming) medication through an IV, but not ketamine.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07639359Recruiting· Phase 2
Ketamine for depression in intensive care patients

This study tests whether low-dose ketamine infusions can reduce depressive symptoms in patients staying in the intensive care unit for at least 6 days. Ketamine is a medication that may work differently than standard antidepressants and could provide faster relief.

Jacksonville, Florida
NCT07590687Not yet recruiting· Phase 3
Ketamine for faster recovery after breathing tube removal

This trial tests if adding ketamine to standard sedation helps people wake up faster and recover better after being on a breathing machine. It may reduce confusion and improve outcomes for critically ill patients.

Paris
NCT05095857Recruiting· Phase 4
Ketamine to improve care in severe acute brain injury

This Phase 4 trial tests whether giving ketamine during anesthesia is safe and helpful for adults with severe sudden brain injuries after surgery. It may improve how patients are sedated and cared for while they are on a breathing machine.

Copenhagen
NCT06750939Recruiting
Comparing two sedatives for ICU breathing tube placement

This study compares two medicines (propofol and ketamine) used to help you relax and stay stable while a breathing tube is placed. The goal is to see which one is safer for your heart and blood pressure during this procedure in the ICU.

Köseköy, Kocaeli
NCT07377981Not yet recruiting· Phase 4
Combination sedative for delirium in ICU patients on breathing support

This trial tests whether combining two sedative medications, esketamine and dexmedetomidine, is safer and more effective than using dexmedetomidine alone for treating hyperactive delirium in ICU patients who need breathing support. If you or a loved one are experiencing severe confusion and agitation while on a breathing machine, this study may offer a new treatment option.

Nanjing, Jiangsu
NCT06468436Not yet recruiting
Calming medicines for ICU patients on a breathing machine

This study tests a combination of two medicines (dexmedetomidine and esketamine) to help ICU patients who are on a breathing machine feel calm and have less pain. The goal is to find a safe and effective way to keep patients comfortable while they recover.

Beijing, Beijing Municipality

Hear when a new Mechanical Ventilation trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.