Clinical trials
Mechanical Ventilation clinical trials
Below are recruiting mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 268 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT06791798Recruiting
Breathing treatments for patients on ventilators
This study tests two breathing treatments—ventilator hyperinflation and chest vibration—to see which works better for clearing mucus and improving lung function in people who have been on a breathing machine for 2 to 7 days.
CairoAges 35–55 - NCT07092943Recruiting
Comparing two breathing methods during surgery
This study tests two ways of using a ventilator during laparoscopic surgery to see which one helps patients breathe better afterward. If you are having elective laparoscopic surgery and need a breathing tube, you may be able to join.
Rawalpindi, Punjab ProvinceAges 16–80 - NCT06655805Recruiting
Registry for automated breathing support in adults
This trial collects data from adults in the ICU who need oxygen therapy, non-invasive ventilation, or a breathing tube with a machine. It looks at how automated settings affect care.
Sankt Gallen, Canton of St. GallenAges 18 years+ - NCT06961227Recruiting
Comparing two breathing machine settings in the ICU
This trial compares two different ways a breathing machine can help you breathe. It uses a special imaging technique to see which method works better for patients in the intensive care unit.
SanliurfaAges 18 years+ - NCT07445035Recruiting
Robotic leg brace to help walking while on a breathing machine
This study tests whether walking with a robotic leg brace (exoskeleton) can help people who are on a breathing machine get better faster. It is for adults in the intensive care unit who can sit, stand with help, and have no major leg or heart problems.
New Taipei CityAges 45–65 - NCT06520605Recruiting
CMV reactivation in ICU patients on ventilators for a week or more
This study looks at whether a common virus called cytomegalovirus (CMV) becomes active again in ICU patients who need a breathing machine for a week or more. It may help doctors understand who is at risk and how to better care for them.
Lucknow, Uttar PradeshAges 18–80 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT03901924Recruiting
Ventilator settings to protect the breathing muscle
This study looks at a specific way to control a breathing machine (ventilator) to help prevent weakness of the diaphragm, the main breathing muscle, in newly intubated adults. You might be considered if you are newly on a ventilator for less than 36 hours and certain other conditions are not present.
Chicago, IllinoisAges 18 years+ - NCT06480162Recruiting
How breathing machines affect the brain's memory center
This trial studies how mechanical ventilation (breathing machine) affects the hippocampus, a part of the brain important for memory. It may help people who already have an electrode in their hippocampus understand how breathing support impacts brain function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07022704Recruiting
Doxapram to help COPD patients breathe easier off the ventilator
This trial tests if the drug doxapram can improve diaphragm movement in COPD patients who are being taken off a ventilator during a breathing trial. It aims to make the transition smoother and more successful.
Cairo, Cairo GovernorateAges 20–65 - NCT07761468Enrolling by invitation
Standardized medication dosing for ICU patients on ventilators
This study is testing a standardized way to adjust a medication used to help people on ventilators in the ICU. It aims to see if a more consistent dosing approach can help patients breathe better and possibly come off the ventilator sooner.
Querétaro City, QuerétaroAges 18 years+ - NCT06482983Recruiting
Two breathing methods for women having laparoscopic gynecologic surgery
This study compares two ways of helping you breathe during surgery to see which one is better for your brain and lungs. The results may help doctors choose the safest method for people like you.
Istanbul, UmraniyeAges 18–70 - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06878703RecruitingPhase 3
Dexmedetomidine vs midazolam for preterm babies on a ventilator
This study compares two sedative medicines, dexmedetomidine and midazolam, to see which one helps preterm babies on a ventilator breathe on their own sooner. Your baby may be eligible if they were born very early and need medicine to relax while on the breathing machine.
ParisAges Up to 7 months - NCT06245317Recruiting
New ventilation method for children having laparoscopic surgery
This trial compares a special ventilation method (PCV-VG) to standard care during laparoscopic surgery in children. It aims to see if it helps them breathe better during the procedure.
Asyut, Asyut GovernorateAges 1–8 - NCT06125210Recruiting
Early treatment bundle to prevent ventilator dependence in kids
This study tests a set of early therapies (a 'bundle') for children on breathing machines to help them get off the machine sooner and avoid long-term dependence. It may be a good fit if your child is stable and doesn't have severe brain or spine problems.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT03736707Recruiting
Testing two breathing machines in very preterm babies
This study compares two ways of helping very preterm infants breathe: a special high-frequency ventilation method versus the standard mechanical ventilator. It aims to see which method works better for preterm babies with breathing failure soon after birth.
Chongqing, Chongqing MunicipalityAges 1 minute–1 hour - NCT05634135Recruiting
Testing breathing and blood-flow patterns in long-term ventilated ICU patients
This study looks at how well air moves through the lungs and how blood flows in different types of patients who have been on a breathing machine for a long time. It may help clinicians better understand these patterns during “weaning” (trying to come off the machine), which could improve care plans.
TaipeiAges 20 years+ - NCT06754670Recruiting
How low phosphate affects breathing after ventilator use
This study looks at how low phosphate levels in the blood affect your ability to breathe on your own when coming off a ventilator. If you are already getting better and ready to start breathing without the machine, the results may help doctors understand and manage your recovery better.
BeijingAges 18 years+ - NCT07750288Recruiting
Understanding breathing difficulty in children with lung injury
This study looks at how severe breathing difficulty (dyspnea) affects the recovery of children with a lung condition called acute respiratory distress syndrome (ARDS). It aims to improve care by tracking symptoms over time.
SantiagoAges 1 month–18 years - NCT06675942Recruiting
Comparing two breathing techniques for patients with excess mucus on ventilators
This trial compares two chest therapy methods to help clear mucus in ICU patients who are on a breathing machine. If you have a lot of mucus and are on a ventilator, this study may test which technique works better.
BeijingAges 18 years+ - NCT07358039Recruiting
Recruitment maneuver after suctioning in ICU patients on ventilators
This study is testing whether a breathing maneuver after suctioning helps restore lung volume in intensive care patients who are on a ventilator. It may help improve breathing and recovery.
Toulon, VARAges 18 years+ - NCT05211661Recruiting
Study breathing muscle changes in people on a ventilator
This study looks at how the diaphragm (a key breathing muscle) changes during and after being on a breathing machine in the ICU. It may help researchers understand why breathing can get weaker after ventilation and how to measure it safely (including with MRI).
AachenAges 18–75
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Mechanical Ventilation trials by city
Studies with a site in or near these metro areas.
Mechanical Ventilation trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for mechanical ventilation?
- Yes. Clin2 currently lists 268 recruiting mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mechanical Ventilation Complication
- Mechanical Ventilation Weaning
- Invasive Mechanical Ventilation
- Mechanical Ventilation Pressure High
- Prolonged Mechanical Ventilation
- Weaning Failure of Mechanical Ventilation
- Weaning Invasive Mechanical Ventilation
- Respiratory Insufficiency Requiring Mechanical Ventilation
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.