Clinical trials
Mechanical Ventilation clinical trials
Below are recruiting mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 251 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07445035Recruiting
Robotic leg brace to help walking while on a breathing machine
This study tests whether walking with a robotic leg brace (exoskeleton) can help people who are on a breathing machine get better faster. It is for adults in the intensive care unit who can sit, stand with help, and have no major leg or heart problems.
New Taipei CityAges 45–65 - NCT06791798Recruiting
Breathing treatments for patients on ventilators
This study tests two breathing treatments—ventilator hyperinflation and chest vibration—to see which works better for clearing mucus and improving lung function in people who have been on a breathing machine for 2 to 7 days.
CairoAges 35–55 - NCT06961227Recruiting
Comparing two breathing machine settings in the ICU
This trial compares two different ways a breathing machine can help you breathe. It uses a special imaging technique to see which method works better for patients in the intensive care unit.
SanliurfaAges 18 years+ - NCT07092943Recruiting
Comparing two breathing methods during surgery
This study tests two ways of using a ventilator during laparoscopic surgery to see which one helps patients breathe better afterward. If you are having elective laparoscopic surgery and need a breathing tube, you may be able to join.
Rawalpindi, Punjab ProvinceAges 16–80 - NCT07022704Recruiting
Doxapram to help COPD patients breathe easier off the ventilator
This trial tests if the drug doxapram can improve diaphragm movement in COPD patients who are being taken off a ventilator during a breathing trial. It aims to make the transition smoother and more successful.
Cairo, Cairo GovernorateAges 20–65 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT06655805Recruiting
Registry for automated breathing support in adults
This trial collects data from adults in the ICU who need oxygen therapy, non-invasive ventilation, or a breathing tube with a machine. It looks at how automated settings affect care.
Sankt Gallen, Canton of St. GallenAges 18 years+ - NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT03901924Recruiting
Ventilator settings to protect the breathing muscle
This study looks at a specific way to control a breathing machine (ventilator) to help prevent weakness of the diaphragm, the main breathing muscle, in newly intubated adults. You might be considered if you are newly on a ventilator for less than 36 hours and certain other conditions are not present.
Chicago, IllinoisAges 18 years+ - NCT07761468Enrolling by invitation
Standardized medication dosing for ICU patients on ventilators
This study is testing a standardized way to adjust a medication used to help people on ventilators in the ICU. It aims to see if a more consistent dosing approach can help patients breathe better and possibly come off the ventilator sooner.
Querétaro City, QuerétaroAges 18 years+ - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06754670Recruiting
How low phosphate affects breathing after ventilator use
This study looks at how low phosphate levels in the blood affect your ability to breathe on your own when coming off a ventilator. If you are already getting better and ready to start breathing without the machine, the results may help doctors understand and manage your recovery better.
BeijingAges 18 years+ - NCT06878703RecruitingPhase 3
Dexmedetomidine vs midazolam for preterm babies on a ventilator
This study compares two sedative medicines, dexmedetomidine and midazolam, to see which one helps preterm babies on a ventilator breathe on their own sooner. Your baby may be eligible if they were born very early and need medicine to relax while on the breathing machine.
ParisAges Up to 7 months - NCT06482983Recruiting
Two breathing methods for women having laparoscopic gynecologic surgery
This study compares two ways of helping you breathe during surgery to see which one is better for your brain and lungs. The results may help doctors choose the safest method for people like you.
Istanbul, UmraniyeAges 18–70 - NCT03736707Recruiting
Testing two breathing machines in very preterm babies
This study compares two ways of helping very preterm infants breathe: a special high-frequency ventilation method versus the standard mechanical ventilator. It aims to see which method works better for preterm babies with breathing failure soon after birth.
Chongqing, Chongqing MunicipalityAges 1 minute–1 hour - NCT06125210Recruiting
Early treatment bundle to prevent ventilator dependence in kids
This study tests a set of early therapies (a 'bundle') for children on breathing machines to help them get off the machine sooner and avoid long-term dependence. It may be a good fit if your child is stable and doesn't have severe brain or spine problems.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT02735707RecruitingPhase 3
Adaptive trial for severe pneumonia care in intensive care
This study tests ways to improve treatment for adults with severe pneumonia that lands them in the ICU, adjusting the plan as results come in. It may help your care team find better treatments for lung infection and breathing/heart support needs.
Jacksonville, FloridaAges 18 years+ - NCT07750288Recruiting
Studying shortness of breath in children with acute respiratory distress
This study looks at how shortness of breath (dyspnea) relates to the progression of pediatric acute respiratory distress syndrome (PARDS), a severe lung condition in children. It aims to understand breathing difficulties better to improve care.
SantiagoAges 1 month–18 years - NCT06675942Recruiting
Comparing two breathing techniques for patients with excess mucus on ventilators
This trial compares two chest therapy methods to help clear mucus in ICU patients who are on a breathing machine. If you have a lot of mucus and are on a ventilator, this study may test which technique works better.
BeijingAges 18 years+ - NCT07372794Recruiting
Lung imaging-guided breathing therapy for patients on ventilators for weeks
This study tests whether using a special lung imaging technique called EIT can help guide breathing exercises and physical therapy for people who have been on a breathing machine for 21 days or more. The goal is to see if this approach helps your lungs work better and speeds up recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07358039Recruiting
Recruitment maneuver after suctioning in ICU patients on ventilators
This study is testing whether a breathing maneuver after suctioning helps restore lung volume in intensive care patients who are on a ventilator. It may help improve breathing and recovery.
Toulon, VARAges 18 years+ - NCT06776939Recruiting
High-flow oxygen through trach tube to help weaning from a ventilator
This trial tests if high-flow oxygen delivered through a tracheostomy tube can make mucus less sticky and reduce breathing effort while you are being taken off a ventilator. It could help you breathe easier during weaning.
RotterdamAges 18 years+ - NCT05211661Recruiting
Diaphragm health during breathing machine support
This study looks at how the diaphragm (the main breathing muscle) changes when a person is on a breathing machine in the intensive care unit. It may help doctors understand how to better support breathing and recovery.
AachenAges 18–75 - NCT06024993Recruiting
Studying dead space in breathing machines during surgery
This trial looks at a part of breathing machines called 'dead space' in adults having planned surgery under general anesthesia. The goal is to learn more about how the lungs work during controlled breathing.
Edegem, AntwerpAges 18–70
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Mechanical Ventilation trials by city
Studies with a site in or near these metro areas.
Mechanical Ventilation trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for mechanical ventilation?
- Yes. Clin2 currently lists 251 recruiting mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mechanical Ventilation Complication
- Mechanical Ventilation Weaning
- Invasive Mechanical Ventilation
- Mechanical Ventilation Pressure High
- Prolonged Mechanical Ventilation
- Weaning Failure of Mechanical Ventilation
- Weaning Invasive Mechanical Ventilation
- Respiratory Insufficiency Requiring Mechanical Ventilation
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.