Ketamine for depression in intensive care patients
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether low-dose ketamine infusions can reduce depressive symptoms in patients staying in the intensive care unit for at least 6 days. Ketamine is a medication that may work differently than standard antidepressants and could provide faster relief.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18–99 years old and have been in the ICU for 6 or more days
- You have moderate to severe depression symptoms (PHQ-9 score of 10 or higher)
- You can understand and agree to participate in the study
- You are medically stable (normal oxygen, blood pressure, heart rate, and breathing rate)
- You weigh between 45 kg and 115 kg (roughly 99–253 pounds)
- You do not have a history of psychosis, hallucinations, dementia, or certain psychiatric conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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