Radiation followed by CAR-T cells for relapsed/refractory DLBCL
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a new two-step treatment: first a small dose of radiation (131I-Apamistamab) followed by specially designed immune cells (CAR-T cells) to fight your lymphoma. It is for people with DLBCL that has relapsed or not responded to standard therapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of lymphoma called diffuse large B-cell lymphoma (DLBCL) or high-grade B-cell lymphoma that has come back or not responded to at least one prior treatment.
- You are 18 years or older.
- Your kidneys, liver, and lungs are working well enough (based on blood tests and oxygen levels).
- Your bone marrow is producing enough healthy blood cells (you have adequate counts of neutrophils, platelets, and hemoglobin).
- You are not pregnant or breastfeeding, and you agree to use effective birth control during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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