New drug plus chemotherapy for advanced pancreatic cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests a new drug called IBI343 combined with standard chemotherapy for people with advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this combination can help shrink tumors or slow the cancer's growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced pancreatic cancer that cannot be removed by surgery or has spread to other parts of the body.
- Your tumor cells must have a protein called CLDN18.2, which will be tested with a small tissue sample.
- You are age 18 or older and your overall health is good enough for daily activities (ECOG score 0 or 1).
- You have at least one tumor that can be measured on scans and has not been previously treated with radiation.
- If you have had chemotherapy before, it has been at least 6 months since your cancer came back or spread.
- You are not pregnant and agree to use effective birth control during and for 6 months after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug, IBI343, combined with chemotherapy for people with advanced pancreatic cancer that has gotten worse after first-line treatment. It looks at whether this combination can help shrink tumors or slow cancer growth.
This study tests a new drug called IBI343 compared to a placebo (inactive substance) for people with advanced pancreatic cancer that has a specific protein (CLDN18.2) and has not responded to earlier treatments. The goal is to see if IBI343 can help slow the cancer's growth.
This trial tests a new form of the chemotherapy drug paclitaxel (called polymeric micellar paclitaxel) for people with pancreatic cancer that has spread to other parts of the body (metastatic). It's for those who haven't had any prior treatment for their metastatic cancer, and aims to see if this drug can help control the cancer.
This study tests a new combination of two drugs for advanced pancreatic cancer. It aims to see if adding an immunotherapy drug (which helps your immune system attack cancer) to standard chemotherapy can help control the cancer better.
This trial studies a new combination of drugs for advanced pancreatic cancer that has spread. The goal is to see if adding the study drug (chiauranib) to standard chemotherapy and immunotherapy can help control the cancer better. It is only for people who have not received prior treatment for their advanced cancer.
This trial tests a new medicine (IBI363) combined with chemotherapy for people with advanced pancreatic cancer that has grown after their first treatment. The goal is to see if this combination can help shrink or control the cancer longer.
Hear when a new Advanced Pancreatic Cancers trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.