Pain relief study for ICU patients on a ventilator
Part of Lungs & breathing clinical trials.
This study tests a painkiller called nalbuphine for ICU patients on a breathing machine. It aims to see if it controls pain as well as or better than usual care, with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You or the patient must be in the ICU and on a breathing machine (ventilator) for more than 6 hours.
- No known allergies to the study painkiller (nalbuphine) or propofol (a common sedative).
- No severe liver or kidney failure, abdominal compartment syndrome, or asthma.
- Not on very high doses of blood pressure medicine (norepinephrine) to keep blood pressure up.
- No major brain or nerve condition that would make it hard to assess pain/sedation levels.
- Not pregnant, breastfeeding, or planning pregnancy in the next 6 months, and not in another trial for 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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