Pain relief study for ICU patients on a ventilator
Part of Lungs & breathing clinical trials.
This study tests a painkiller called nalbuphine for ICU patients on a breathing machine. It aims to see if it controls pain as well as or better than usual care, with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You or the patient must be in the ICU and on a breathing machine (ventilator) for more than 6 hours.
- No known allergies to the study painkiller (nalbuphine) or propofol (a common sedative).
- No severe liver or kidney failure, abdominal compartment syndrome, or asthma.
- Not on very high doses of blood pressure medicine (norepinephrine) to keep blood pressure up.
- No major brain or nerve condition that would make it hard to assess pain/sedation levels.
- Not pregnant, breastfeeding, or planning pregnancy in the next 6 months, and not in another trial for 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two pain relievers, hydromorphone and nalbuphine, given through a patient-controlled pump after cesarean section. It aims to find which provides better pain control with fewer side effects.
This study tests a pain medicine called hydromorphone for people in the ICU who need a breathing tube. The goal is to see how well it works and if it's safe for managing pain and sedation.
This trial tests a pain medicine called oxycodone for patients on breathing machines in the ICU. It aims to see if it provides safe and effective long-term pain control.
This study compares different pain medicines for patients in the ICU who are not on a breathing machine. It aims to find which approach works best for moderate to severe pain while keeping patients safe.
This study looks at a new way to measure pain in ICU patients who are on a breathing machine (ventilator) and receiving strong pain medicine (opioids). The goal is to see if adjusting pain medicine based on a special pain assessment tool can improve comfort and recovery.
This trial tests if the drug nalbuphine can help patients with acute respiratory distress syndrome (ARDS) after surgery. It aims to see if it improves breathing and pain while staying in the ICU.
Hear when a new Respiratory Insufficiency trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.