Clinical trials
Respiratory Insufficiency clinical trials
Below are recruiting respiratory insufficiency clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07071935RecruitingPhase 2
Early ventilation study for newly diagnosed ALS
This trial tests whether starting non-invasive ventilation (breathing support) early in ALS helps people breathe easier and live better. If you've been diagnosed with ALS in the last 6 months and haven't used a breathing machine before, you may qualify.
Hershey, PennsylvaniaAges 18 years+ - NCT07730034Recruiting
Early physical therapy after heart surgery to prevent breathing problems
This trial tests whether starting physical therapy soon after planned heart surgery can help prevent breathing complications. It is for adults who are having a first-time coronary artery bypass grafting (CABG) and meet specific health criteria.
ZagrebAges 18–80 - NCT05913882Recruiting
Breathing training for people with ALS to improve cough
This study tests a breathing and expiratory muscle training program to help people with ALS cough more effectively. It may help reduce breathing and airway trouble by strengthening the muscles used for cough in early-stage ALS.
Fort Lauderdale, FloridaAges 18–90 - NCT06675045Recruiting
High flow oxygen therapy and breathing patterns
This study looks at how breathing changes in patients with low blood oxygen levels who are treated with high-flow oxygen through a mask. It aims to understand which patients might need a breathing tube.
MarseilleAges 18 years+ - NCT07170085Recruiting
Positioning for babies with breathing problems
This trial tests if different body positions help babies under 1 year old with breathing problems breathe better while on oxygen support (High-Flow or CPAP).
OdenseAges Up to 1 year - NCT06756633Recruiting
Breathing and movement study for neuromuscular disease
This study looks at breathing, chest and belly movement, and exercise ability in people with Duchenne Muscular Dystrophy or Spinal Muscular Atrophy, as well as healthy people. The goal is to compare these functions to help understand how these diseases affect the body.
Ankara, ÇankayaAges 5–15 - NCT06510972Recruiting
Eating versus fasting for ICU patients with breathing failure
This study looks at whether it's safe and helpful to let people with severe breathing problems in the ICU eat and drink normally instead of fasting. If you qualify, you may be assigned to either continue eating or to fast while doctors monitor your recovery.
BloisAges 18 years+ - NCT04524585Recruiting
Tested a muscle-relaxing treatment for severe low-oxygen breathing
This study tests whether partially relaxing the breathing-related muscles can help people with severe low oxygen while they are on a breathing machine. It may improve how well the lungs work by changing the way the muscles affect breathing.
Toronto, OntarioAges 18 years+ - NCT04626154Recruiting
Testing a device for breathing problems during chest movement
This study looks at how well a special device can be used in children to understand breathing problems related to chest and belly movement. It may help researchers improve care for kids who have breathing distress.
Boston, MassachusettsAges 4 weeks–17 years - NCT07188038Recruiting
Comparing low vs high breathing tube pressure on diaphragm health
This trial compares two levels of positive end-expiratory pressure (PEEP) in patients on a breathing machine. It looks at how these pressures affect diaphragm function, how well the lungs work, and how efficiently you breathe.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT07839949Recruiting
Monitoring breathing effort during ventilator weaning
This study tests a new, non-invasive way to monitor how hard your breathing muscles are working while the ventilator support is being reduced. It aims to help doctors wean you off the ventilator more smoothly and safely.
Palma de Mallorca, Balearic IslandsAges Any age - NCT07633288RecruitingPhase 2
AP1189 Safety and Efficacy for Severe Respiratory Viral Infection
This trial tests whether an experimental drug called AP1189, added to standard hospital care, can help people hospitalized with severe breathing problems from viruses like COVID-19, flu, or RSV. The goal is to see if it reduces the need for mechanical ventilation or other life support.
Mostar, Herzegovina-Neretva CantonAges 18 years+ - NCT06841341Enrolling by invitation
Predicting breathing problems in ALS
This study uses ultrasound and electrical tests of breathing muscles and nerves to see if they can predict breathing failure in people with ALS. This could help doctors know when a patient might need breathing support.
Krakow, Lesser Poland VoivodeshipAges 18–80 - NCT05642832Recruiting
Test a breathing-device method to reduce breathing effort
This trial checks whether a special “through-flow” system can safely reduce how hard your body has to breathe when you are on a breathing machine. It is mainly a feasibility study, meaning the focus is on whether the approach can be done safely and effectively.
Toronto, OntarioAges 18 years+ - NCT04430790RecruitingPhase 3
Doxapram for apnea in very preterm babies on breathing support
This trial studies whether the medicine doxapram can better treat breathing pauses (apnea) in very preterm babies who are already on breathing support in the NICU. It aims to reduce the need for extra interventions and improve outcomes in this high-risk group.
Brussels, Avenaue Hippocrate 10Ages 5 months–7 months - NCT06442267RecruitingPhase 4
Comparing blood thinners for ECMO support
This trial compares three different blood thinners (heparin, argatroban, and enoxaparin) used during ECMO support. It aims to find the safest and most effective way to prevent blood clots while on ECMO.
Vienna, State of ViennaAges 18 years+ - NCT07571317Recruiting
Predicting breathing tube removal success in ICU patients
This study tests whether two simple breathing measurements can predict whether patients in the ICU are ready to have their breathing tube removed. If successful, it could help doctors make safer decisions about when patients can breathe on their own.
Istanbul, IstanbulAges 18 years+ - NCT06785571RecruitingPhase 2/Phase 3
Pain relief study for ICU patients on a ventilator
This study tests a painkiller called nalbuphine for ICU patients on a breathing machine. It aims to see if it controls pain as well as or better than usual care, with fewer side effects.
Wuhan, HubeiAges 18–80 - NCT07468006Recruiting
Comparing carbon dioxide measurements in critically ill children
This trial tests if a sticker on the skin can accurately measure carbon dioxide levels in the blood, reducing the need for needle sticks in children in the intensive care unit.
BrnoAges 1–18 - NCT05906030Recruiting
Ultrasound to study diaphragm function around surgery
This trial uses ultrasound (a non-painful scanning method) to measure how well the diaphragm works around the time of surgery. It aims to learn whether diaphragm changes during surgery relate to breathing problems, especially in people undergoing abdominal, pelvic, or vascular operations.
Stockholm, Stockholm CountyAges 18–100 - NCT07422441Recruiting
Guided abdominal wall closure for large hernia repair
This trial tests a new way to close the abdominal wall after surgery for a large hernia, using lung compliance measurements to guide the closure. It aims to improve recovery by finding the best closure technique for each patient.
GdanskAges 18 years+ - NCT06844370Recruiting
Home vs hospital NIV care for MND
This study compares two ways of starting non-invasive ventilation (NIV) — a breathing machine — for people with motor neurone disease (MND). It aims to see if starting NIV at home is as safe and effective as starting it in the hospital.
CambridgeAges 18 years+ - NCT06819943Recruiting
Bed positioning to reduce pressure on the body
This study tests a special bed positioning technique (lateralization therapy) to see if it lowers pressure on the body and helps prevent bedsores in people on breathing machines. If you are on a ventilator and not yet ready to breathe on your own, this trial may help improve your comfort and skin health.
São Paulo, São PauloAges 18 years+ - NCT06655805Recruiting
Registry for automated breathing support in adults
This trial collects data from adults in the ICU who need oxygen therapy, non-invasive ventilation, or a breathing tube with a machine. It looks at how automated settings affect care.
Sankt Gallen, Canton of St. GallenAges 18 years+
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Respiratory Insufficiency trials by city
Studies with a site in or near these metro areas.
Common questions
- Are there clinical trials for respiratory insufficiency?
- Yes. Clin2 currently lists 30 recruiting respiratory insufficiency studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory insufficiency trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory insufficiency trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.