Clinical trials
Respiratory Insufficiency clinical trials
Below are recruiting respiratory insufficiency clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07071935RecruitingPhase 2
Early ventilation study for newly diagnosed ALS
This trial tests whether starting non-invasive ventilation (breathing support) early in ALS helps people breathe easier and live better. If you've been diagnosed with ALS in the last 6 months and haven't used a breathing machine before, you may qualify.
Hershey, PennsylvaniaAges 18 years+ - NCT07730034Recruiting
Early physical therapy after heart surgery to prevent breathing problems
This trial tests whether starting physical therapy soon after planned heart surgery can help prevent breathing complications. It is for adults who are having a first-time coronary artery bypass grafting (CABG) and meet specific health criteria.
ZagrebAges 18–80 - NCT06494215Recruiting
Comparing methods to measure lung air distribution in ventilated patients
This study tests different ways to measure how air is distributed in the lungs of patients on a breathing machine (ventilator) as they are being weaned off. It may help doctors better understand lung function during recovery.
São PauloAges 18 years+ - NCT05913882Recruiting
Breathing training for people with ALS to improve cough
This study tests a breathing and expiratory muscle training program to help people with ALS cough more effectively. It may help reduce breathing and airway trouble by strengthening the muscles used for cough in early-stage ALS.
Fort Lauderdale, FloridaAges 18–90 - NCT06675045Recruiting
High flow oxygen therapy and breathing patterns
This study looks at how breathing changes in patients with low blood oxygen levels who are treated with high-flow oxygen through a mask. It aims to understand which patients might need a breathing tube.
MarseilleAges 18 years+ - NCT07170085Recruiting
Positioning for babies with breathing problems
This trial tests if different body positions help babies under 1 year old with breathing problems breathe better while on oxygen support (High-Flow or CPAP).
OdenseAges Up to 1 year - NCT06756633Recruiting
Breathing and movement study for neuromuscular disease
This study looks at breathing, chest and belly movement, and exercise ability in people with Duchenne Muscular Dystrophy or Spinal Muscular Atrophy, as well as healthy people. The goal is to compare these functions to help understand how these diseases affect the body.
Ankara, ÇankayaAges 5–15 - NCT04524585Recruiting
Tested a muscle-relaxing treatment for severe low-oxygen breathing
This study tests whether partially relaxing the breathing-related muscles can help people with severe low oxygen while they are on a breathing machine. It may improve how well the lungs work by changing the way the muscles affect breathing.
Toronto, OntarioAges 18 years+ - NCT04626154Recruiting
Testing a device for breathing problems during chest movement
This study looks at how well a special device can be used in children to understand breathing problems related to chest and belly movement. It may help researchers improve care for kids who have breathing distress.
Boston, MassachusettsAges 4 weeks–17 years - NCT06510972Recruiting
Eating versus fasting for ICU patients with breathing failure
This study looks at whether it's safe and helpful to let people with severe breathing problems in the ICU eat and drink normally instead of fasting. If you qualify, you may be assigned to either continue eating or to fast while doctors monitor your recovery.
BloisAges 18 years+ - NCT03515031Recruiting
Compare two oxygen masks for breathing failure from pneumonia
This trial compares two ways of giving oxygen—high-flow nasal tubes versus a Venturi face mask—for adults with pneumonia causing acute breathing failure. It aims to see which method works better to improve breathing and recovery.
BergamoAges 18 years+ - NCT07633288RecruitingPhase 2
AP1189 Safety and Efficacy for Severe Respiratory Viral Infection
This trial tests whether an experimental drug called AP1189, added to standard hospital care, can help people hospitalized with severe breathing problems from viruses like COVID-19, flu, or RSV. The goal is to see if it reduces the need for mechanical ventilation or other life support.
Mostar, Herzegovina-Neretva CantonAges 18 years+ - NCT06841341Enrolling by invitation
Predicting breathing problems in ALS
This study uses ultrasound and electrical tests of breathing muscles and nerves to see if they can predict breathing failure in people with ALS. This could help doctors know when a patient might need breathing support.
Krakow, Lesser Poland VoivodeshipAges 18–80 - NCT05642832Recruiting
Test a breathing-device method to reduce breathing effort
This trial checks whether a special “through-flow” system can safely reduce how hard your body has to breathe when you are on a breathing machine. It is mainly a feasibility study, meaning the focus is on whether the approach can be done safely and effectively.
Toronto, OntarioAges 18 years+ - NCT05857774Recruiting
Study breathing muscle changes in ICU patients on ventilation
This study looks at how the muscles used for breathing work and change in ICU patients who are placed on breathing machines, then follows outcomes after they leave the hospital. It may help doctors better predict recovery and long-term health after ventilation.
Toronto, OntarioAges 18 years+ - NCT06655805Recruiting
Registry for automated breathing support in adults
This trial collects data from adults in the ICU who need oxygen therapy, non-invasive ventilation, or a breathing tube with a machine. It looks at how automated settings affect care.
Sankt Gallen, Canton of St. GallenAges 18 years+ - NCT07468006Recruiting
Comparing carbon dioxide measurements in critically ill children
This trial tests if a sticker on the skin can accurately measure carbon dioxide levels in the blood, reducing the need for needle sticks in children in the intensive care unit.
BrnoAges 1–18 - NCT04430790RecruitingPhase 3
Doxapram for apnea in very preterm babies on breathing support
This trial studies whether the medicine doxapram can better treat breathing pauses (apnea) in very preterm babies who are already on breathing support in the NICU. It aims to reduce the need for extra interventions and improve outcomes in this high-risk group.
Brussels, Avenaue Hippocrate 10Ages 5 months–7 months - NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Tucson, ArizonaAges 18 years+ - NCT05500833Recruiting
Studying breathlessness in children to better understand symptoms
This study looks closely at why children feel short of breath (“dyspnea”) and how breathing symptoms change over time. Your child may help doctors improve understanding and care for breathing problems like asthma or other lung conditions.
ParisAges 6–17 - NCT05906030Recruiting
Ultrasound to study diaphragm function around surgery
This trial uses ultrasound (a non-painful scanning method) to measure how well the diaphragm works around the time of surgery. It aims to learn whether diaphragm changes during surgery relate to breathing problems, especially in people undergoing abdominal, pelvic, or vascular operations.
Stockholm, Stockholm CountyAges 18–100 - NCT06102330Recruiting
Helping parents decide about home breathing machines
This study helps parents like you who are deciding whether their child should have a breathing machine at home. You'll use a website or get support by phone to learn about your options and share what matters most to your family, so doctors and families can make better choices together.
Tampa, FloridaAges 18 years+ - NCT06442267RecruitingPhase 4
Comparing blood thinners for ECMO support
This trial compares three different blood thinners (heparin, argatroban, and enoxaparin) used during ECMO support. It aims to find the safest and most effective way to prevent blood clots while on ECMO.
Vienna, State of ViennaAges 18 years+ - NCT06483984Recruiting
Testing facemasks to remove carbon dioxide in breathing trouble
This trial tests special facemasks that help remove carbon dioxide from the blood during noninvasive breathing support (like a CPAP or BiPAP mask). It is for people who have a sudden breathing problem with high carbon dioxide and low blood pH.
RomaAges 18 years+
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Respiratory Insufficiency trials by city
Studies with a site in or near these metro areas.
Common questions
- Are there clinical trials for respiratory insufficiency?
- Yes. Clin2 currently lists 30 recruiting respiratory insufficiency studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory insufficiency trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory insufficiency trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.