Cord blood cells for poor graft function after transplant
Treatments studied
Part of Blood & lymphatic clinical trials.
This study tests whether umbilical cord blood cells can help patients whose blood counts have dropped again after a stem cell transplant. It may be an option for people who have recovered initially but later develop low blood cell levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You have had a stem cell transplant and your blood counts initially recovered, but then dropped again for more than 2 weeks.
- Your bone marrow exam shows the transplant is still working and your original disease is in remission.
- You are in generally good health (able to care for yourself).
- You do not have uncontrolled infections, serious heart, liver, or kidney problems, or another active cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving extra stem cells from your original donor can help your blood cell counts recover after a transplant. It is for people whose new immune system has not fully engrafted or whose counts are dangerously low.
This trial studies whether giving decitabine and donated umbilical cord blood can improve blood count recovery when a transplant is not working well. It is for people who have poor graft function at least 28 days after an allogeneic transplant and meet several safety and disease-status conditions.
This trial tests if a single dose of umbilical cord blood cells can help patients whose blood counts stay dangerously low after CAR-T or antibody therapy. It aims to reduce the need for transfusions and improve recovery.
This study tests a modified second stem cell transplant for people whose first transplant failed. It uses half-matched (haploidentical) donor cells to try to restore healthy blood cells and treat the cancer.
This trial tests a second transplant using two donated umbilical cord blood units for people whose blood cancer returned after a first stem cell transplant. It aims to offer a potential cure for high-risk blood cancers.
This study tests whether using cord blood stem cells (collected from umbilical cords after birth) can help treat high-risk blood cancers in children and young adults when a matched donor is not quickly available. Cord blood transplants may help prevent cancer from coming back.
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