Cord blood cells for poor graft function after transplant
Treatments studied
Part of Blood & lymphatic clinical trials.
This study tests whether umbilical cord blood cells can help patients whose blood counts have dropped again after a stem cell transplant. It may be an option for people who have recovered initially but later develop low blood cell levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You have had a stem cell transplant and your blood counts initially recovered, but then dropped again for more than 2 weeks.
- Your bone marrow exam shows the transplant is still working and your original disease is in remission.
- You are in generally good health (able to care for yourself).
- You do not have uncontrolled infections, serious heart, liver, or kidney problems, or another active cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving extra stem cells from your original donor can help your blood cell counts recover after a transplant. It is for people whose new immune system has not fully engrafted or whose counts are dangerously low.
This trial tests whether adding a medicine called decitabine along with an umbilical cord blood infusion can help improve blood counts in people whose counts are not recovering well after a stem cell transplant. It aims to boost your body's ability to make healthy blood cells.
This trial tests whether a drug called decitabine can help improve poor graft function after a donor stem cell transplant. Poor graft function means your blood counts stay low because the donor stem cells are not working well enough. Decitabine may help stimulate the bone marrow to produce more blood cells.
This study tests whether umbilical cord blood cells can help people whose blood counts stay dangerously low after immune-based cancer treatments like CAR-T or bispecific antibodies. The treatment aims to boost your blood cell recovery and reduce the need for transfusions.
This study tests a modified second stem cell transplant for people whose first transplant failed. It uses half-matched (haploidentical) donor cells to try to restore healthy blood cells and treat the cancer.
This study tests whether giving special stem cells (called mesenchymal stem cells) can help improve poor graft function after a stem cell transplant. It aims to boost your blood cell counts so you recover better.
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