Pain relief after knee replacement: injection methods compared
Part of Pain clinical trials.
This study compares two ways to give pain medicine during knee replacement surgery: one is injected into the bone, the other around the joint. Researchers want to see which works better and may help you recover with less pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 80 years old.
- You are having a total knee replacement on one side only (not both knees at once).
- Your health status is classified as ASA 1, 2, or 3 (generally meaning you are in good to moderate health).
- You do not have severe kidney, liver, or blood problems, and have not had a seizure disorder, coronary heart disease, or recent blood clots.
- You have not used opioid pain medicines in the 5 days before surgery, and are not on blood thinners or anti-platelet medicines.
- You can understand and use a 0–10 pain scale (the 100mm VAS) and are willing to follow the study plan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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