Comparing two knee pain relief methods after replacement
Part of Bones, joints & muscles, Brain & nervous system, Pain clinical trials.
This study compares two ways to manage pain after knee replacement surgery: a special nerve block (iPACK) versus a shot of medicine around the knee joint. The goal is to see which method gives better pain relief and helps you recover faster.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for a first-time, one-sided total knee replacement because of arthritis.
- Your overall health is classified as ASA II or III (your anesthesiologist can tell you this).
- You do not take strong painkillers (opioids) every day.
- You do not have nerve damage in the leg that will be operated on.
- You do not have severe kidney or liver problems.
- You are not allergic to the pain medicines used in the study (like local anesthetics, ibuprofen, or morphine).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two ways to give pain medicine during knee replacement surgery: one is injected into the bone, the other around the joint. Researchers want to see which works better and may help you recover with less pain.
This trial tests two different types of nerve blocks to see which one provides better pain relief after a total knee replacement. The blocks are given during surgery to help manage pain afterward.
This study compares two different ways of giving a nerve block (called iPACK) to see which works better for pain after total knee replacement. The goal is to find the best spot for the injection to help you feel more comfortable after surgery.
This study tests two different nerve-block techniques to see which provides better pain control after total knee replacement surgery. The goal is to help you recover more comfortably.
This study compares two different nerve-blocking anesthesia techniques to see which one controls pain better after knee replacement surgery. Both methods are designed to numb the area around your knee so you need less pain medication afterward.
This trial compares two different ways of numbing the leg to provide better pain relief after total knee replacement surgery. It tests whether adding a popliteal sciatic nerve block (behind the knee) to a saphenous block (inner thigh) works better than adding an IPACK block (back of the knee).
Hear when a new Pain, Postoperative trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.