Pulsed-field ablation for non-paroxysmal atrial fibrillation
Part of Heart & circulation clinical trials.
This trial tests a new way to treat non-paroxysmal atrial fibrillation (AF) using a focused type of ablation (pulsed-field energy) on specific areas of the heart. It aims to see if targeting the left atrial wall and mitral isthmus can improve outcomes for people who have not had this procedure before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with non-paroxysmal atrial fibrillation (persistent or long-standing AF).
- Your doctor has recommended a catheter ablation (a treatment to fix the heart's electrical signals).
- You must be willing to sign a consent form to participate.
- You cannot have had a previous ablation in the left upper chamber of your heart.
- You cannot have kidney disease stage 3 or worse, or a blood disorder that causes red blood cells to break down.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a new way to do a heart procedure (catheter ablation) for people with ongoing atrial fibrillation (an irregular heartbeat). It uses pulsed-field energy to create a block in the heart that stops abnormal electrical signals. The goal is to improve the procedure's success and reduce risks.
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This study tests a special catheter that uses pulsed field energy to ablate (destroy) the tiny areas in the heart causing irregular heartbeats. It is designed for people with paroxysmal atrial fibrillation (episodes that come and go) that hasn't been controlled by medication.
This study tests a newer, gentler way to fix irregular heartbeats in people with paroxysmal AF. The treatment uses special energy (pulsed fields) guided by 3D imaging to target the heart tissue causing the problem, and the goal is to restore a normal rhythm with fewer risks.
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