Clinical trials
Severe Infection clinical trials
Below are recruiting severe infection clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04923828Recruiting
Study drug resistance in very sick children with infections
This trial enrolls children in the pediatric intensive care unit (PICU) who have a severe infection. It aims to better understand germs and drug resistance so future treatments can be more effective.
Shanghai, Shanghai MunicipalityAges 1 month–16 years - NCT04990908Recruiting
Screening children in ICU for immune problems after severe infection
This study checks children in pediatric intensive care for possible “immune system problems” after a severe infection. The goal is to find primary immunodeficiencies early, which may change follow-up and treatment for the child’s immune health.
MontpellierAges 3 months–16 years - NCT06185920Recruiting
A study of phage therapy for severe infections
This study looks at how well phage therapy (a virus that kills bacteria) works for severe infections. It's for people who received this treatment at a specific hospital in France.
LyonAges Any age - NCT05536219Recruiting
Study how autoantibodies affect virus levels in severe lung infections
This study measures blood immune “autoantibodies” that may affect how much virus is in the body during severe respiratory infections. It may help doctors understand which patients are more likely to have higher virus levels and could guide future treatment choices.
Bron, RhoneAges Any age - NCT06178822Recruiting
New blood tests to diagnose sepsis in the ER
This study aims to find new ways to quickly diagnose sepsis (a severe response to infection) in patients arriving at the emergency room. If successful, these new tests could help doctors start treatment faster.
Almere Stad, FlevolandAges 18 years+ - NCT07111793Recruiting
Study of severe bacterial infections in children
This study looks at children who had a severe bacterial infection in the past to understand why some get very sick. It may help find better ways to prevent or treat these infections in the future.
Nantes, Loire AtlantiqueAges Any age - NCT04650607Recruiting
Phage therapy safety check in serious infection patients
This study checks the safety of using phage therapy (viruses that target certain bacteria) in adults being treated for serious infections. If you meet the safety rules, your care team may enroll you to help confirm phage treatment is safe.
LyonAges 18 years+ - NCT06260345Recruiting
Children with severe bacterial infections in intensive care
This trial looks at how children with severe bacterial infections that start outside the hospital are treated in the pediatric intensive care unit. It helps doctors learn more about these infections to improve care for kids.
CréteilAges Up to 18 years - NCT04961593Recruiting
Studying caspofungin dosing in very ill children
This study looks at how caspofungin works in children who are very sick and in the pediatric intensive care unit. It helps doctors better choose dosing to keep the medicine at the right level.
Shanghai, Shanghai MunicipalityAges 3 months–18 years - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT04178915Enrolling by invitation
Blood marker study to predict severe bacterial lung infection
This study looks at specific immune cells and how fats are transported in the blood to predict which people will have a severe bacterial infection (like pneumonia or sepsis). Your results may help doctors identify higher-risk patients earlier.
MinskAges 18–60 - NCT06102044RecruitingPhase 3
Zinc for young infants with severe infection in Tanzania
This study tests whether giving zinc supplements to very young babies (under 2 months) with severe infections helps them recover better. It takes place in Tanzania and involves adding zinc to their regular care.
Dar es SalaamAges birth–2 months - NCT04955210Recruiting
Study of data sharing in children with severe infections
This trial builds a shared medical data system to better understand severe pneumonia and sepsis in children. Your participation helps clinicians and researchers learn from many cases to improve future care.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT07694648Recruiting
Watching for germs that cause breathing problems
This study tracks patients with breathing problems to see which germs are making them sick. Doctors will use tests and medical records to watch for different pathogens.
Beijing, Beijing MunicipalityAges Any age - NCT07523646RecruitingPhase 4
Blood Boost for Patients With Heart Valve Infections
This study tests whether giving iron and a blood-boosting medicine (EPO) helps patients with bacterial heart valve infections who have low red blood cells. The goal is to see if it speeds recovery and improves how patients feel.
CopenhagenAges 18 years+ - NCT07113951Enrolling by invitation
AI-ROSE for diagnosing severe pneumonia
This trial uses an AI tool called AI-ROSE to analyze lung fluid from a bronchoscopy. It aims to help doctors quickly diagnose severe pneumonia and guide treatment.
Nanjing, JiangsuAges 18 years+ - NCT05645107RecruitingPhase 3
XEMBIFY plus usual care to prevent infections
This Phase 3 study tests whether XEMBIFY (an immune protein therapy) plus standard medical treatment can better prevent serious or repeated infections. It is for people with certain cancers of blood/immune systems who are already having trouble with infections.
Huntington Park, CaliforniaAges 18 years+ - NCT05788861Recruiting
Study for children with severe strep skin or bloodstream infection
This trial is for people under 18 who have a confirmed invasive Group A strep infection, meaning strep bacteria found in places that are normally sterile (like the blood or deep tissues). It tests whether a specific study approach can help improve outcomes for children with these serious infections.
CréteilAges 1 day–17 years - NCT07206745Recruiting
Chinese and Western medicine for severe pneumonia from drug-resistant bacteria
This trial tests a combination of traditional Chinese and Western medicine for adults with severe pneumonia caused by bacteria that are resistant to multiple antibiotics. It aims to see if this combined approach can improve treatment outcomes.
Zhengzhou, HenanAges 18–80 - NCT05888987Recruiting
New test for severe corneal infection diagnosis
This study tests a new method for identifying bacteria causing severe corneal infections. It may help doctors choose the right treatment faster by improving how the infection is identified from corneal samples.
ReimsAges 18 years+ - NCT03044223Recruiting
Profiles of immune cells in severe Pseudomonas sepsis
This study looks at patterns of immune cells in people who are critically ill with sepsis caused by Pseudomonas aeruginosa bacteria. It may help doctors better understand how the immune system responds and improve care for this serious infection.
UlmAges 18–90 - NCT05369052RecruitingPhase 3
New antibiotic for moderate or severe diabetic foot infections
This Phase 3 trial tests a new medicine (contezolid acefosamil, and contezolid) to treat moderate or severe diabetic foot infections. It compares the new treatment to linezolid to see which works better and is safer for adults.
Corona, CaliforniaAges 18 years+ - NCT02498587Recruiting
Study of severe breathing illness over a short period
This study looks at people who recently had fever and cough along with trouble breathing, to better understand severe acute respiratory illness. By joining, you may help researchers identify patterns that could improve recognition and care.
Melbourne, VictoriaAges Any age - NCT06490744Recruiting
Lung function after COVID-19 in lung transplant patients
This study looks at how lung function changed over time in lung transplant patients who had a moderate to severe COVID-19 infection. It may help doctors understand how to better care for transplant patients after a serious COVID-19 illness.
StrasbourgAges 18 years+
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Common questions
- Are there clinical trials for severe infection?
- Yes. Clin2 currently lists 62 recruiting severe infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.