Nasal spray COVID-19 vaccine booster study for healthy adults
Part of Infections, Lungs & breathing clinical trials.
This study tests a new nasal spray COVID-19 vaccine to see how it compares to an mRNA booster shot. It is for healthy adults who have already had at least 3 doses of an mRNA COVID-19 vaccine (or 2 doses plus a confirmed COVID infection) and are looking for a needle-free booster option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 55 years old (phase 1) or 60 years old (phase 2).
- You have a body mass index (BMI) between 18.5 and 30, meaning a healthy weight range.
- You have already had at least 3 doses of an mRNA COVID-19 vaccine, with your last booster at least 6 months ago. Or you had 2 mRNA doses and a confirmed COVID infection at least 6 months ago.
- You are in good general health, with no serious medical conditions like chronic rhinitis (stuffy nose), nasal problems, or a history of nosebleeds.
- You are available to stay near the study site for the whole trial and agree to use barrier methods (like masks and hand washing) against COVID-19.
- If you are a woman who can become pregnant, you must use highly effective birth control and not be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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