Long-term endurance training for sickle cell disease
Part of Blood & lymphatic, Genetic & congenital clinical trials.
This study tests whether a long-term endurance exercise program can improve physical fitness, reduce complications, and enhance quality of life for people with sickle cell disease. It is designed for patients whose condition is stable but who have had at least one pain crisis in the last three years.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 15 years and 3 months old
- You have sickle cell disease (HbSS or HbS-beta thal0)
- You are in a stable condition, which means no blood transfusion in the last 3 months and no recent crisis or infection in the last month
- You have been hospitalized for a vaso-occlusive crisis at least once in the last 3 years
- You do not currently do regular exercise (more than 1 hour of moderate activity per week)
- You have no other chronic inflammatory or infectious disease, and no heart condition requiring a pacemaker or blood thinners
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether a personalized exercise and nutrition program can help people with sickle cell disease feel better and have fewer pain crises. It is for adults 35 and older with any type of sickle cell disease.
This early-phase study tests whether a “half-matched” donor bone marrow transplant, with special medicines to calm the immune system before transplant, can improve outcomes for people with sickle cell disease. It may help high-risk patients who have frequent complications and don’t have a fully matched donor.
This trial tests CS-206, an experimental therapy for people with sickle cell disease. It aims to reduce severe complications like pain crises, acute chest syndrome, strokes, and other serious events. You may qualify if you have a specific genetic type of sickle cell disease and have experienced complications despite standard treatments.
This study helps connect adults with sickle cell disease who haven't seen a specialist in over a year back into care. It tests a program designed to make it easier to get regular medical support and improve your health.
This trial tests whether a half-matched (haploidentical) blood stem cell transplant can treat adults with severe sickle cell disease. It may help reduce serious complications and improve survival, but it requires a fit health status and specific donor and medical conditions.
This study looks at whether regular red blood cell exchange (a treatment that replaces sickled red blood cells with healthy ones) can reduce blood clotting and inflammation in people with sickle cell disease. It aims to see if this treatment helps protect your blood vessels.
Hear when a new Sickle Cell Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.