Comparing biologics for chronic sinusitis with nasal polyps
Part of Ear, nose & throat, Infections, Lungs & breathing clinical trials.
This trial compares three different biologic medications (injectable drugs) to see which one works best for people with chronic sinusitis and nasal polyps. If you have moderate to severe symptoms and are considering biologic therapy, this study might help find the best option for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with chronic sinusitis and nasal polyps (confirmed by a doctor using standard criteria).
- You have a polyp score of 5 or higher (on a scale of 0 to 8).
- Your SNOT-22 symptom score is above 30 (meaning moderate to severe symptoms).
- You are willing to try one of three biologic medications and have not had them before.
- You have been using a daily nasal steroid spray (like mometasone) for at least one month.
- You have not had sinus surgery in the last 6 months, and have not used oral steroids in the last 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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