Study of invikafusp alfa plus sacituzumab govitecan for advanced solid tumors
Treatments studied
Part of Cancer, Women’s health & pregnancy clinical trials.
This trial tests a new drug combination for people with advanced breast cancer (triple-negative or hormone receptor-positive). The goal is to see if the combination helps shrink tumors or slow their growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced breast cancer that is either triple-negative or HR+/HER2- and has gotten worse after treatment.
- Your cancer can be measured on a CT scan or MRI.
- If you have brain metastases, they must be treated and stable without needing high-dose steroids for at least 2 weeks.
- You do not have an active autoimmune disease (except mild skin conditions like vitiligo or psoriasis not requiring strong medication).
- You have not had major surgery or an unhealed wound in the past 8 weeks.
- You are not pregnant or breastfeeding, and you are willing to use effective birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study is testing a drug called sacituzumab govitecan (SG) for people with advanced triple-negative breast cancer who have already had other treatments. The goal is to see how well the drug works and what side effects it causes, using your tumor samples to look for clues (biomarkers).
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