Study of a new drug for cardiogenic shock in intensive care
Part of Heart & circulation clinical trials.
This trial tests an investigational drug called invobenitug for people in cardiogenic shock, a condition where the heart can't pump enough blood. The drug may help improve blood flow and reduce the need for strong blood pressure medicines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You are currently in the intensive care unit (ICU) and have been there for less than 24 hours.
- You need medicines (vasopressors or inotropes) to keep your blood pressure up, and you've been on them for 16 hours or less.
- You have a high level of DPP3 (a protein linked to heart problems) in your blood.
- Your shock is caused by a heart attack, sepsis (severe infection), or advanced heart failure.
- You are not pregnant or breastfeeding, and you do not have severe organ failure or other critical conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether an inotrope medicine (a drug that helps the heart pump) works better than a placebo in adults in intensive care with cardiogenic shock. It may help doctors find safer, more effective treatment for this life-threatening condition.
This trial tests an investigational drug called istaroxime for people hospitalized with acute heart failure and low blood pressure (cardiogenic shock). The drug aims to improve heart function and stabilize blood pressure, potentially helping you feel better and recover.
This trial tests if unloading the heart during ECMO support helps patients recover better from cardiogenic shock. It compares different ways to reduce the heart's workload.
This study tracks how well people with cardiogenic shock (a life-threatening drop in blood flow after a heart attack or heart failure worsening) do when treated with modern support devices and medicines.
This trial is testing different approaches (medications and mechanical support) to help people with acute heart failure and cardiogenic shock (a sudden drop in the heart's pumping ability). It looks at how well these treatments work in a network of hospitals to improve outcomes.
This study looks at people with a severe type of shock that affects both the heart and blood vessels, treated in the intensive care unit. It aims to understand how these patients recover and what factors impact their survival.
Hear when a new Shock, Cardiogenic trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.