IV IgG for collagen VII antibodies in dystrophic epidermolysis bullosa
Part of Genetic & congenital, Skin clinical trials.
This trial tests if intravenous immunoglobulin (IV IgG) can help people with a form of epidermolysis bullosa who have antibodies against collagen VII. It may reduce blistering and improve wound healing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have recessive dystrophic epidermolysis bullosa (RDEB) confirmed by genetic testing
- You have antibodies to collagen VII above normal levels
- You have active blistering covering more than 5% of your body
- You have at least one wound that is at least 20 square cm and can be treated with Vyjuvek weekly
- You have at least one other wound of the same size that has never been treated with Vyjuvek
- You are currently receiving Vyjuvek treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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