Clinical trials
Dystrophic Epidermolysis Bullosa clinical trials
Below are recruiting dystrophic epidermolysis bullosa clinical trials, each written for real people, not researchers. We’re tracking 14 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07482787RecruitingPhase 3
Study of SD-101 for epidermolysis bullosa in children
This trial tests a new medicine called SD-101 for children with epidermolysis bullosa (EB), a condition that causes fragile skin and blistering. It aims to see if SD-101 can help heal wounds and improve quality of life.
Rancho Santa Margarita, CaliforniaAges 4 weeks–12 years - NCT06594393RecruitingPhase 2
Testing TCP-25 Gel for Epidermolysis Bullosa
This trial tests a gel called TCP-25 on wounds caused by a specific type of epidermolysis bullosa (DEB or JEB). It aims to see if the gel can help heal wounds and improve comfort.
Cincinnati, OhioAges 4 years+ - NCT07700966Recruiting
Long-term safety registry for EB treatment
This study follows patients who have already received a gene therapy treatment called prademagene zamikeracel for a severe skin condition called recessive dystrophic epidermolysis bullosa (RDEB). The goal is to track long-term safety and health outcomes after treatment.
Palo Alto, CaliforniaAges Any age - NCT04173650RecruitingPhase 1/Phase 2
Testing stem cell “package” therapy for severe skin blistering
This early-stage study tests stem cell–derived “extra-cellular vesicles” (small natural cell packages) to help heal painful skin wounds in people with dystrophic epidermolysis bullosa (DEB). If you have suitable, untreated wounds and meet the safety requirements, you may be able to join and help researchers learn whether this treatment is beneficial.
Phoenix, ArizonaAges 6 months+ - NCT04917887Recruiting
Gene therapy long-term follow-up for Krystal Biotech patients
This study follows people who previously received a gene therapy from Krystal Biotech to better understand long-term safety and outcomes. If you already had their gene therapy before and you can keep follow-up appointments, you may be able to join.
Rancho Santa Margarita, CaliforniaAges 6 months+ - NCT06177353Recruiting
Immune study in recessive dystrophic epidermolysis bullosa and stem cells
This study looks at the immune system in people with recessive dystrophic epidermolysis bullosa (RDEB) and tests how placental stem cells affect immune cells in the lab. It aims to understand the disease better and explore potential treatments.
ParisAges 18–80 - NCT06423573Recruiting
Skin cancer risk in epidermolysis bullosa patients using Filsuvez
This study tracks anyone with dystrophic or junctional epidermolysis bullosa who is using Filsuvez gel to see how often skin cancers appear. It is designed to understand the long-term safety of the treatment.
ToulouseAges Any age - NCT06563414Recruiting
A study tracking eye scrapes in people with DEB
This study follows people with dystrophic epidermolysis bullosa (DEB) who get scrapes on the surface of their eye (corneal abrasions). It collects information to better understand how often and how severely these eye injuries happen.
Pittsburgh, PennsylvaniaAges 6 months+ - NCT06834035RecruitingPhase 1/Phase 2
IV IgG for collagen VII antibodies in dystrophic epidermolysis bullosa
This trial tests if intravenous immunoglobulin (IV IgG) can help people with a form of epidermolysis bullosa who have antibodies against collagen VII. It may reduce blistering and improve wound healing.
Redwood City, CaliforniaAges 6 years+ - NCT06917690RecruitingPhase 3
Testing oleogel-S10 for epidermolysis bullosa in Japanese patients
This trial tests a gel called oleogel-S10 on wounds caused by a rare skin condition called epidermolysis bullosa (EB). It is only for people of Japanese descent who have a specific type of EB called junctional or dystrophic EB. The gel is put on the wound to help it heal.
FukuokaAges 3 weeks+ - NCT07016750RecruitingPhase 3
Study of KB803 eye drops for eye scrapes in DEB
This study tests an experimental eye drop (KB803) to see if it can reduce painful scrapes on the surface of the eye in people with dystrophic epidermolysis bullosa. You would be randomly assigned to receive either the study drops or a placebo (an inactive drop) for several months.
Rancho Santa Margarita, CaliforniaAges 6 months+ - NCT07193134RecruitingPhase 1/Phase 2
Gene-modified skin graft for RDEB
This trial tests a new skin graft made with your own cells that have been genetically modified to produce a missing protein (collagen 7). It's for people with RDEB, a severe blistering condition, and aims to see if the graft can heal wounds safely.
Toronto, OntarioAges 7 years+ - NCT07230223RecruitingPhase 1/Phase 2
A study of Ev.FV on wound healing in dystrophic epidermolysis bullosa
This trial tests if a drug called Ev.FV can help heal wounds in people with dystrophic epidermolysis bullosa (DEB), a condition that causes fragile, blistering skin. It is for people with open wounds on their arms, legs, or trunk that are a specific size.
IsfahanAges 3–35 - NCT01019148Recruiting
Study of people with recessive dystrophic epidermolysis bullosa
This study looks at the medical features and needs of people who have recessive dystrophic epidermolysis bullosa (RDEB). It may help doctors better understand the condition and plan better care.
Stanford, CaliforniaAges Any age
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Dystrophic Epidermolysis Bullosa trials by city
Studies with a site in or near these metro areas.
Dystrophic Epidermolysis Bullosa trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for dystrophic epidermolysis bullosa?
- Yes. Clin2 currently lists 14 recruiting dystrophic epidermolysis bullosa studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dystrophic epidermolysis bullosa trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dystrophic epidermolysis bullosa trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.