Smell function in chronic sinusitis patients
Part of Ear, nose & throat clinical trials.
This study looks at how changes in a small area inside the nose (called the olfactory cleft) affect smell in people with chronic sinusitis. It aims to understand why some people with sinusitis have trouble smelling, which could lead to better treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have chronic sinusitis (inflammation of the sinuses that lasts more than 12 weeks) and be scheduled for sinus surgery.
- You must be able to understand the study and give your written consent.
- You should not have taken certain medications in the last 4 weeks (like oral steroids, antibiotics, or allergy pills).
- You should not have had sinus surgery in the past.
- You must not have other nasal conditions like fungal infections, tumors, or a weakened immune system that could affect your nose.
- You need to be able to do smell tests (physically and mentally).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if a special way of using budesonide (a steroid) as nose drops can improve your sense of smell. It's for people with chronic sinusitis and smell loss, and aims to see if this treatment can help restore some ability to smell.
This study tests whether smell training can improve your sense of smell and affect your immune system. It is for people with chronic sinus inflammation and nasal polyps who have lost their sense of smell.
This study is a registry that collects information from people with chronic rhinosinusitis (CRS) to test new criteria for measuring how well the disease is controlled, if it goes into remission, or if it's cured. It's a real-world study, meaning it looks at how treatments work in everyday life, and participation just involves providing data over time.
This study tests a special smell training program to see if it helps improve your sense of smell after sinus surgery. The training involves regularly smelling different scents to help your nose recover.
This study aims to develop a new way to stage a type of chronic sinusitis with nasal polyps (CCAD) using CT scans, which may help doctors better understand and treat the condition.
This trial tests whether steroid nose drops placed in the upper part of the nose, combined with smell training (sniffing different scents), can help people who lost their sense of smell after an infection. The goal is to see if this combination improves smell recovery better than training alone.
Hear when a new Chronic Rhinosinusitis (CRS) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.