Nasal drops with budesonide for smell loss in sinusitis
Part of Ear, nose & throat clinical trials.
This study tests if a special way of using budesonide (a steroid) as nose drops can improve your sense of smell. It's for people with chronic sinusitis and smell loss, and aims to see if this treatment can help restore some ability to smell.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have chronic sinusitis (ongoing inflammation of the sinuses) and you've had trouble smelling for at least 12 weeks.
- Your doctor has confirmed signs of a specific type of inflammation (Type 2) through blood tests or a sinus CT scan.
- You have not used oral steroids in the past 4 weeks, nasal steroid sprays in the past 2 weeks, or biologic injections (like dupilumab) in the past 6 months.
- You are not pregnant and do not plan to become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a special smell training program to see if it helps improve your sense of smell after sinus surgery. The training involves regularly smelling different scents to help your nose recover.
This study looks at how changes in a small area inside the nose (called the olfactory cleft) affect smell in people with chronic sinusitis. It aims to understand why some people with sinusitis have trouble smelling, which could lead to better treatments.
This study tests a nasal spray made from mastic oil combined with a lower dose of a standard steroid medication (mometasone) for people with chronic sinusitis. It aims to see if this combination is effective in reducing symptoms.
This study tests whether smell training can improve your sense of smell and affect your immune system. It is for people with chronic sinus inflammation and nasal polyps who have lost their sense of smell.
This study is looking at how the brain processes smells in people with chronic sinusitis and nasal polyps who have a reduced sense of smell. It will compare brain images (MRI) of patients who are starting biologic treatment and those who are not, to understand how these medications might affect the brain.
This study tests a special nose dressing that slowly releases a steroid to reduce inflammation and improve healing after sinus surgery for chronic sinusitis with or without nasal polyps.
Hear when a new Chronic Rhinosinusitis (CRS) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.