Combination Chemotherapy for Advanced Small Bowel Cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of chemotherapy drugs (NALIRIFOX) for people with advanced small bowel adenocarcinoma that cannot be surgically removed. It is for those who have not yet had treatment for their advanced cancer, except possibly one cycle of FOLFOX.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of small bowel cancer called adenocarcinoma that has spread and cannot be surgically removed.
- Your tumor is mismatch repair proficient (MMRp) or microsatellite stable (MSS).
- You have not had prior treatment for advanced disease (except possibly one cycle of FOLFOX).
- You are generally active (ECOG 0 or 1) and have adequate organ function as checked by blood tests and heart rhythm.
- You are 18 years or older and willing to use effective contraception if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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