Chemotherapy for unremovable small bowel cancer
Part of Cancer clinical trials.
This trial tests two standard chemotherapy combinations (FOLFIRINOX and FOLFOX) in people with small bowel adenocarcinoma that cannot be removed by surgery or has spread. It aims to see which works better for people who haven't had chemotherapy before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your cancer is a type called adenocarcinoma, and it started in your small intestine (duodenum, jejunum, or ileum).
- Your tumor cannot be removed by surgery, or it has spread to other parts of your body.
- You have not had chemotherapy for this cancer before.
- Your tumor must be measurable (able to be seen on scans).
- You must be 18 or older and be able to understand and sign a consent form.
- If you are age 70 or younger, your daily activity level should score 0, 1, or 2. If over 70, it should be 0 or 1.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two types of chemotherapy to see which works better after surgery for ampullary cancer. One treatment is a stronger combination (FOLFIRINOX), and the other is a single drug (capecitabine or gemcitabine). It is for people whose cancer was completely removed by surgery and who have no spread to other organs.
This trial tests a combination of chemotherapy drugs (NALIRIFOX) for people with advanced small bowel adenocarcinoma that cannot be surgically removed. It is for those who have not yet had treatment for their advanced cancer, except possibly one cycle of FOLFOX.
This trial studies a more customized treatment plan for people with locally advanced rectal (bowel) cancer after they receive FOLFIRINOX chemotherapy. It aims to reduce tumor spread risk and improve outcomes by tailoring the next steps based on scan details and your health status.
This Phase 2 study tests chemotherapy given before surgery (called FOLFIRINOX) for people with locally advanced stomach cancer. The goal is to shrink the tumor and improve outcomes after the surgery plan is completed.
This trial tests a combination of two chemotherapy drugs, levozolinate and 5-FU, given together as a first treatment for advanced colorectal cancer that cannot be surgically removed. It aims to see if giving them at the same time works better for patients who have never received treatment for this stage of cancer.
This trial tests two different chemotherapy regimens (FOLFOX8 and mFOLFOX6), each paired with a targeted drug (bevacizumab or cetuximab), to treat colorectal cancer that has spread and cannot be surgically removed. The goal is to find which combination works best as a first treatment.
Hear when a new Locally Advanced or Metastatic Small Bowel Adenocarcinoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.