Nerve surgery for pain after cancer amputation
Part of Cancer, Injuries & trauma, Pain clinical trials.
This study tests two surgical techniques—target muscle re-innervation and regenerative peripheral nerve interfaces—alone or together, to help reduce pain felt in the remaining limb or the missing limb (phantom pain) after amputation for cancer. The goal is to find the best way to manage pain and improve quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- Your amputation is being done because of cancer.
- You have healthy nerves available in the area of the amputation that can be used for the surgery.
- You are able to give your informed consent to participate.
- You are expected to live longer than 3 months so the surgery has time to work.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at nerve pain in children and teens who had an amputation before a certain age. It aims to understand how common and how severe this pain is after amputation, and uses simple questionnaires to find out.
This trial tests a new nerve surgery technique to help people with above-knee leg amputations have better control of their prosthetic leg. The goal is to improve how well the prosthesis responds to your movements.
This study tests if adding a nerve stimulation device to a standard nerve block provides better pain relief after below-knee amputation. You may be eligible if you are having this surgery and do not have certain other medical conditions.
This study evaluates how well nerve surgery works for patients with severe, persistent pain in the area where a limb was amputated. Researchers will review outcomes to understand if this surgical approach helps reduce pain that hasn't responded to other treatments.
This trial tests a surgical procedure called targeted muscle reinnervation (TMR) to prevent pain after a leg amputation. The goal is to see if rerouting nerves during amputation can reduce phantom limb pain or stump pain.
This trial studies different surgical approaches to reduce persistent pain in the leftover part of an amputated limb. You may be able to join if your post-amputation pain has lasted more than a year and your pain level stays high despite stable pain treatments and prosthesis use.
Hear when a new Amputation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.