Pumitamig plus chemo for Stage IV lung cancer after immunotherapy
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a new investigational drug called Pumitamig (BNT327) given with chemotherapy for people with advanced non-small cell lung cancer (Stage IV) that has continued to grow after one prior treatment with immunotherapy and platinum chemotherapy. The study aims to see if this combination is safe and can help shrink the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Stage IV lung cancer that has grown after one prior treatment that included both immunotherapy and platinum chemotherapy.
- You have not had more than one prior treatment for advanced lung cancer (adjuvant doesn't count if it was more than 6 months ago).
- Your PD-L1 test results (a marker on your cancer cells) must be available from a previous test.
- You can be up and about (daily activities fine or only limited by heavy work).
- You have not had prior treatment with docetaxel (a certain chemotherapy) or drugs that block blood vessel growth (like Avastin).
- You do not have a serious wound, fistula, or high bleeding risk.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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