Clin2
NCT06843902Possibly a fitRecruiting

Improving heart blood flow in women with HIV

HIV-1-infectionCoronary Microvascular DysfunctionMetabolic Disease

Part of Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.

This study is testing a medication that may help improve blood flow to the heart in women with HIV who also have diabetes, kidney disease, or protein in their urine. You would need to have a heart scan that shows low blood flow and not be taking certain diabetes drugs.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
80 people
Ages
45 years to 75 years
Study type
Interventional

Who can take part

  • You are a woman (assigned female at birth) and between 45 and 75 years old.
  • You have HIV and have been on the same HIV medications for at least 6 months.
  • You have at least one of these: type 2 diabetes, moderately reduced kidney function (eGFR 30-60), or protein in your urine.
  • You have a heart PET scan that shows your heart's blood flow is lower than normal (less than 2.5).
  • You are not currently taking an SGLT2 inhibitor (like empagliflozin or dapagliflozin) and have no allergy to it.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04055428Recruiting· Phase 2
Testing a hormone supplement to improve heart and metabolic health

This study tests whether adding a natriuretic peptide medicine improves heart health and metabolism in Black adults. It may help with blood pressure and related health markers, but you must meet specific health and safety criteria.

Birmingham, Alabama
NCT05129345Recruiting
HIV care program for heart health goals in the Southeast US

This trial tests an approach to help people living with HIV reach heart- and metabolism-related health goals, such as blood pressure, cholesterol, and blood sugar. It involves clinics and community partners and may offer education, support, and care coordination to remove barriers to treatment.

Charlotte, North Carolina
NCT05459077Not yet recruiting
Improving blood pressure medication use for people with HIV

This study looks at ways to help people living with HIV stay on their blood pressure (hypertension) medicines consistently. It may help improve blood pressure control and reduce barriers to taking medications as prescribed.

Durham, North Carolina
NCT07105007Recruiting
Heart health program for older adults living with HIV

This study tests a special program to help people living with HIV improve their heart health through activity and healthy habits. If you have early signs of heart trouble and are not currently very active, this support may help you feel better and reduce your risk.

Seattle, Washington
NCT07186153Not yet recruiting
Study of a diabetes drug on heart changes in diabetic patients

This study tests whether a type of diabetes medication called an SGLT2 inhibitor can improve the structure and function of the heart's left atrium in people with type 2 diabetes. It may help prevent heart problems in the future.

NCT07237451Recruiting
Heart and kidney study of SGLT2 inhibitors

This study looks at whether a type of diabetes medicine called SGLT2 inhibitors (also known as flozins) can help protect the heart and kidneys in people with both heart failure with preserved pumping function and moderate chronic kidney disease, with or without diabetes.

Iași

Hear when a new HIV-1-infection trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.