Clin2
NCT07273838Possibly a fitRecruiting

SGLT2 inhibitor for acute heart and kidney failure

Heart FailureAcute Kidney Injury

Treatments studied

Part of Heart & circulation, Kidney & urinary, Women’s health & pregnancy clinical trials.

This study tests whether a medicine called an SGLT2 inhibitor (which lowers blood sugar and helps the kidneys) can improve outcomes for people with acute heart failure and kidney problems. Participation involves taking the study drug or a placebo for a short time.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
130 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You are 18 to 85 years old.
  • You have been diagnosed with heart failure and are currently having symptoms of worsening heart failure.
  • You are not on dialysis and do not have severe kidney disease (eGFR less than 25).
  • You are able to take pills by mouth and follow the study schedule.
  • You have not taken an SGLT2 inhibitor (like empagliflozin or dapagliflozin) in the last 72 hours.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06528405Recruiting· Phase 2
SGLT2 inhibitor study for acute kidney disease patients

This study tests whether SGLT2 inhibitors (a type of diabetes drug that also helps kidneys) can help patients with acute kidney disease. It may be an option if you have diabetes or chronic kidney disease along with acute kidney problems.

Taipei
NCT06929169Recruiting· Phase 2
SGLT2 inhibitor heart health study in dialysis patients

This study tests whether a medicine called an SGLT2 inhibitor (a type of diabetes drug also used for heart failure) affects the heart and blood vessels in people with kidney failure who are on dialysis. It will help doctors understand if this medicine is safe and helpful for dialysis patients.

Buenos Aires, Buenos Aires
NCT05392764Recruiting· Phase 3
SGLT2 medicine for high-risk people after sudden worsening heart failure

This Phase 3 trial tests whether starting an SGLT2 inhibitor early in the hospital can improve outcomes for people at high risk after acute (sudden) heart failure. If you qualify, you would be randomized to receive the study medicine or standard care, started within 12 hours of admission.

Anjo, Aichi-ken
NCT06982079Recruiting· Phase 3
SGLT2 inhibitors for advanced kidney disease

This trial tests whether SGLT2 inhibitor drugs can protect kidney function in people with advanced chronic kidney disease who are not yet on dialysis. It may help slow further kidney decline.

Cairo
NCT06030843Recruiting· Phase 2/Phase 3
Testing empagliflozin for heart and kidney health

This trial tests if the drug empagliflozin can improve kidney function in people hospitalized with heart failure who also develop acute kidney injury. It may help protect the kidneys while treating the heart condition.

Bangkok, Pathumwan
NCT07351643Not yet recruiting· Phase 4
Heart scan study of a diabetes drug for non-diabetic heart attack patients

This trial tests whether a diabetes medication, called an SGLT2 inhibitor, can reduce inflammation around heart arteries in people who have had a heart attack but do not have diabetes. The study uses a special heart scan to look at changes over time.

Shenyang, Liaoning

Hear when a new Heart failure trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.