Clin2
NCT06844422Possibly a fitRecruiting

Guided radiation plus chemo and immune drug for pancreatic cancer

Pancreatic Cancer

Treatments studied

Part of Cancer, Digestive system, Hormones & metabolism clinical trials.

This study tests whether a new combination of super-precise radiation (guided SBRT), standard chemotherapy, and a newer immune medicine called Ivonescimab can slow or shrink pancreatic tumors that cannot be removed by surgery. The goal is to find a more effective treatment option.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
37 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have a type of pancreatic cancer that has not spread to other parts of the body but cannot be removed with surgery.
  • You are between 18 and 80 years old.
  • You are able to do most of your daily activities on your own (not bedridden).
  • Your doctor estimates you will live at least 3 more months.
  • Your blood counts (red cells, white cells, platelets) and liver/kidney function are within a certain healthy range.
  • You must be willing to provide tissue and blood samples for research.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07683221Not yet recruiting· Phase 2
SBRT plus immunotherapy and chemotherapy for advanced pancreatic cancer

This trial tests a combination of radiation therapy (SBRT), two immunotherapy drugs (Ipilimumab and Sintilimab), and two chemotherapy drugs (Nab-Paclitaxel and Gemcitabine) for people with locally advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this treatment can control the cancer better than standard options.

Jinan, Shandong
NCT06991491Not yet recruiting· Phase 2
Ivonescimab with chemo and radiation for metastatic pancreatic cancer

This trial tests a combination of the immunotherapy drug Ivonescimab, chemotherapy (GnP), and stereotactic body radiation therapy (SBRT) for people with metastatic pancreatic cancer. It aims to see if this combo can help shrink tumors and improve outcomes.

NCT06491472Recruiting· Phase 2
Ivonescimab with radiation and chemo for pancreatic cancer

This trial tests a new immunotherapy drug (ivonescimab) combined with targeted radiation and chemotherapy for people with pancreatic cancer. The goal is to see if this combination can shrink tumors and improve outcomes.

Wuhan
NCT06953999Recruiting· Phase 3
Testing immunotherapy plus chemo for metastatic pancreatic cancer

This trial tests a new immunotherapy drug called ivonescimab combined with chemotherapy, with or without another experimental drug (AK117), for people with pancreatic cancer that has spread. The goal is to see if adding these therapies can help shrink tumors or slow the cancer's growth.

Harbin, Heilongjiang
NCT06944106Recruiting· Phase 2
Ivonescimab plus chemo before surgery for pancreatic cancer

This trial tests whether adding the drug ivonescimab to chemotherapy before surgery can help people with borderline resectable pancreatic cancer. The treatment is given for a short time to shrink the tumor and make surgery more likely to succeed.

Tianjin, Tianjin Municipality
NCT07325214Not yet recruiting
IMD10 ultrasound plus chemo for pancreatic cancer

This trial tests whether adding focused ultrasound (IMD10) to standard chemotherapy helps treat pancreatic cancer that is borderline or locally advanced and cannot be removed by surgery right away. It may shrink the tumor enough to allow surgery later.

Boston, Massachusetts

Hear when a new Pancreatic cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.