Combination therapy before surgery for advanced mouth cancer
Part of Cancer, Mouth & dental clinical trials.
This trial tests a combination of two drugs (benmelstobart and anlotinib) given with standard chemotherapy before surgery in people with advanced mouth cancer. The goal is to see if this combination can shrink the tumor and improve the chance of successful treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You need a type of mouth cancer called squamous cell carcinoma that hasn't been treated yet and is at stage III or IVb.
- You should be able to do most of your normal daily activities (performance status 0 or 1).
- You cannot have had immunotherapy (like PD-1/PD-L1 inhibitors) before.
- You need to be in good health—no serious heart, liver, kidney, or bleeding problems, and no other active cancer in the past 3 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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