Comparing two creams for multiple actinic keratoses
Part of Cancer, Skin clinical trials.
This study compares a cream with fluorouracil alone to a cream with fluorouracil plus calcipotriene for people with several actinic keratoses (a type of rough, precancerous spot caused by sun damage). The goal is to see if the combination works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older and not able to become pregnant (postmenopausal, surgically sterilized, or had ovaries/uterus removed).
- You must have between 4 and 15 actinic keratoses (sun spots that feel rough) in one connected area on your head, neck, arm, or hand that is at least 2.5 by 2.5 inches.
- You must be able to start treatment within one week of joining the study.
- You cannot have any wounds or suspected skin cancer within 2 inches of the area to be treated.
- You cannot be taking certain other skin creams, oral medications for skin conditions, or have a weakened immune system.
- You cannot have a history of high calcium levels or vitamin D toxicity.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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