Clin2
NCT06853496Possibly a fitRecruiting

RK-582 for advanced colorectal cancer

Unresectable Colorectal Neoplasm Metastasis

Part of Cancer, Digestive system clinical trials.

This trial tests a new type of pill called RK-582 that may help block the growth of colorectal cancer cells. It is for people whose cancer has spread and hasn't gotten better with other treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
48 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have colorectal cancer that has spread to other parts of the body and can't be removed by surgery.
  • Standard treatments for this cancer have stopped working or caused severe side effects.
  • You have at least one tumor that can be measured by scans (like CT or MRI).
  • You can swallow capsules by mouth.
  • You do not have a history of certain lung problems, blood clots, or brittle bones (osteoporosis).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06824064Recruiting· Phase 2
RBS2418 for advanced metastatic colorectal cancer

This trial tests a new drug called RBS2418 for people with advanced colorectal cancer that has spread and is getting worse, even after other treatments have stopped working. The goal is to see if RBS2418 can help control the cancer.

Newark, Delaware
NCT07515820Not yet recruiting· Phase 2
SHR-3821 for Advanced Colorectal Cancer That Didn't Respond to Prior Treatment

This study tests a new drug called SHR-3821 in patients with colorectal cancer that has spread or come back after at least two rounds of standard chemotherapy. The goal is to see if this drug can slow or shrink the cancer.

NCT06462183Recruiting· Phase 1
Study of RGT-61159 for Advanced ACC or CRC

This trial tests a new drug called RGT-61159 for adults with adenoid cystic carcinoma or colorectal cancer that has returned or stopped responding to treatment. The goal is to see if the drug is safe and effective in shrinking tumors.

Boston, Massachusetts
NCT05319314Recruiting· Phase 1/Phase 2
Study drug for advanced colon cancer that has come back or failed

This Phase 1/2 trial tests LYL273, a new targeted treatment, for people with metastatic colorectal (colon) cancer that has returned or not responded to standard chemo. It’s designed to see how well the drug can control the cancer and what side effects it causes.

Duarte, California
NCT07498725Recruiting· Phase 1/Phase 2
Study of LRK-4189 for solid tumors that have spread or can't be removed

This trial tests a new drug called LRK-4189, alone or with other treatments, for people with advanced solid tumors that have worsened despite prior therapy. The goal is to see if it is safe, tolerable, and helpful against the cancer.

Nice
NCT06373133Not yet recruiting· Phase 1/Phase 2
Investigational drug combo for advanced colorectal cancer

This trial tests a new combination of three drugs for people with advanced colorectal cancer that has not responded to previous treatments. The goal is to see if this combination can help shrink tumors or slow the cancer's growth.

Hear when a new Unresectable Colorectal Neoplasm Metastasis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.