Clin2
NCT06854029Possibly a fitNot yet recruiting

Optimizing HIV prevention and opioid treatment in jail

HIV InfectionsOpioid Use DisorderIncarceration; Lens

Treatments studied

Part of Immune system & allergy, Infections, Mental health clinical trials.

This study tests whether a combination of buprenorphine (a medication for opioid addiction) and PrEP (a daily pill to prevent HIV) can help people who are leaving jail or prison stay healthy. It aims to reduce both opioid relapse and HIV risk during the transition back to the community.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
450 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are at least 18 years old and in one of the study jails or prisons.
  • You are likely to be released within 120 days.
  • You have a moderate or severe opioid use disorder (or were treated for it in the past year).
  • You do not have HIV (confirmed by a test).
  • You are willing to take both buprenorphine (for opioid addiction) and PrEP (to prevent HIV) and be assigned to one of two treatment groups.
  • You will be living in a study area after release.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05669534Recruiting· Phase 4
HIV prevention support for people starting PrEP

This study tests how to better support HIV prevention for people who inject drugs and are newly starting PrEP (medicine to prevent HIV). It focuses on people taking medication for opioid use disorder and who have mild thinking and memory problems, to help them stay safe and adhere to prevention.

New Haven, Connecticut
NCT05769218Recruiting
Rapid HIV prevention and opioid treatment access for people who inject

This study helps people who inject drugs start HIV prevention (PrEP) and medication for opioid use disorder (MOUD) faster. It may reduce HIV risk and improve access to treatment, while the study checks whether the “rapid access” approach works.

Boston, Massachusetts
NCT05547048Recruiting· Phase 4
Phone-based support to help prevent HIV in justice-involved women

This study tests an integrated phone-based health program (e-health) designed for women involved with the justice system who have opioid use disorder. It aims to help people who qualify for HIV prevention (PrEP) stay protected, especially by using simple, ongoing support through phone access.

Birmingham, Alabama
NCT06501781Recruiting
PUSH: Helping People with HIV and Substance Use

This study tests if a program that encourages positive activities (behavioral activation) can help people with HIV or on PrEP who also use substances improve their health. It focuses on those receiving long-acting injectable medications for HIV prevention or treatment.

Washington D.C., District of Columbia
NCT03135886Recruiting
Testing for HIV in opioid treatment programs

This project studies how to improve offering and completing HIV (and hepatitis C) tests in opioid treatment programs. It may help increase timely follow-up and linkage to care when results are positive.

New York, New York
NCT06962033Recruiting
Pride III: Prison and HIV prevention study

This study looks at ways to improve HIV prevention and treatment for people on probation who have injected opioids. Researchers want to learn from your experiences to help create better services.

New Haven, Connecticut

Hear when a new HIV Infections trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.