Testing a sleep drug for suicide risk in veterans with depression
Treatments studied
Part of Mental health clinical trials.
This trial tests whether a medication called suvorexant (used for sleep) can help lower suicide risk in veterans who have major depression and have attempted suicide before. The study aims to see if blocking a brain chemical called orexin reduces suicidal thoughts.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a veteran
- You are between 18 and 70 years old
- You have major depressive disorder (diagnosed by a doctor)
- You have tried to kill yourself in the past and currently have thoughts of suicide
- You are not taking certain medications (ask the study team for details)
- You do not have active substance abuse, bipolar disorder, OCD, or a psychotic disorder
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests different medication combinations in adults with major depressive disorder who are also having suicidal thoughts. It aims to find a more effective and safer treatment approach for this serious condition.
This trial tests an investigational medication for adults with major depressive disorder who are currently taking an antidepressant but still have symptoms. It aims to see if adding this new drug can improve mood better than a placebo.
This study tests whether the sleep medication suvorexant can improve insomnia in veterans who also have post-traumatic stress disorder (PTSD). It aims to see if treating sleep helps with PTSD symptoms.
This trial tests suvorexant, a sleep medicine, to help improve sleep disturbance in people with PTSD. It’s designed for adults who have had PTSD symptoms for at least a few months and also have insomnia.
This study tests whether the sleep medication suvorexant (Belsomra) can help people with opioid use disorder who also have trouble sleeping. If you are stable on medication for opioid use disorder and have not used opioids in the last month, this trial may be an option for you.
This study tests a new sleep medication (an orexin antagonist) to see if it helps Veterans with PTSD overcome fear and sleep better. It aims to improve how your brain handles fear responses.
Hear when a new Suicide Risk trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.