Clin2
NCT07602153Possibly a fitNot yet recruiting

Multimodal drug study for major depression with suicidal thoughts

Major Depressive Disorder (MDD

Part of Mental health clinical trials.

This study tests different medication combinations in adults with major depressive disorder who are also having suicidal thoughts. It aims to find a more effective and safer treatment approach for this serious condition.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
130 people
Ages
18 years to 65 years
Study type
Observational

Who can take part

  • You are between 18 and 65 years old.
  • You are of Han Chinese descent.
  • You have a diagnosis of major depressive disorder (MDD) and are currently having thoughts of suicide.
  • You have completed primary school or higher education.
  • You are not pregnant or breastfeeding, and do not have unstable physical health conditions.
  • You have no history of drug or alcohol abuse in the past 6 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06891300Recruiting· Phase 2/Phase 3
Ketamine for Suicidal Thoughts in Depression

This study tests if ketamine can help reduce suicidal thoughts in people with major depression. You'll receive ketamine treatment and be monitored closely.

Ottawa, Ontario
NCT07139106Not yet recruiting· Phase 4
Ketamine for suicidal thoughts in depression

This study tests whether ketamine can help reduce suicidal thoughts in people with depression. It also looks at how ketamine affects a brain receptor that may be linked to mood and stress, to learn why it might help.

New York, New York
NCT07801703Not yet recruiting· Phase 2/Phase 3
Ketamine and therapy for treatment-resistant depression

This study combines behavioral activation therapy (a type of counseling that helps you re-engage in positive activities) with ketamine infusions to treat depression that hasn't improved with standard antidepressants. The goal is to see if adding this therapy makes ketamine work better and last longer.

Ottawa, Ontario
NCT06788249Recruiting· Early Phase 1
Ketamine for treatment-resistant depression brain study

This trial tests whether a single dose of ketamine can quickly improve depression by studying brain chemical changes using MRI. It's for people with treatment-resistant depression who haven't used ketamine before.

Philadelphia, Pennsylvania
NCT07569198Recruiting· Phase 2
Ketamine plus therapy for depression with suicidal thoughts

This study tests whether ketamine (a medication) combined with a specific type of therapy called DBT can help people with treatment-resistant depression and borderline personality disorder who are having thoughts of suicide. You would receive ketamine infusions alongside structured therapy sessions over 6 months.

Toronto, Ontario
NCT07741240Not yet recruiting· Phase 3
New medicine for major depressive disorder in adults

This study tests an investigational drug called KH607 for adults with major depressive disorder (MDD). It aims to see if the drug can reduce depression symptoms over time. Participants must stop other depression medications before starting and will be monitored closely.

Hear when a new Major Depressive Disorder (MDD trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.