Carvedilol for high blood pressure in liver veins
Treatments studied
Part of Digestive system, Heart & circulation clinical trials.
This trial tests whether a medicine called carvedilol can lower high blood pressure in the liver veins of people with cirrhosis. It uses a special ultrasound probe to measure the pressure before and after taking the medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have cirrhosis of the liver with signs of high blood pressure in the liver veins (portal hypertension), as shown by certain tests or by having varicose veins in your esophagus that are at risk of bleeding.
- You have never taken a beta-blocker medicine (like propranolol or carvedilol) for your liver condition.
- You are covered by French health insurance.
- You do not have severe heart problems, severe lung disease, severe liver complications, active cancer, or a blood clot in the liver vein in the last 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether carvedilol can prevent the first development of swollen veins (varices) in the esophagus in people with cirrhosis who do not have them yet. It may help lower the risk of future bleeding from those veins.
This trial tests if metformin can lower the pressure in the liver's blood vessels (portal hypertension) in people with cirrhosis. The goal is to see if it can help reduce complications like swelling or bleeding.
This trial tests whether adding endoscopic banding helps prevent bleeding from enlarged varices in people with cirrhosis who still have high-risk varices despite taking carvedilol.
This study is checking if it is safe for people with cirrhosis (liver scarring) to stop taking a certain blood pressure medicine (non-selective beta blockers) if their main liver problem is under control. If you've had varices or bleeding in the past and your liver is now stable, this trial will see if you can safely stop the medicine.
This trial is for people with liver cirrhosis who have high blood pressure in the vein that carries blood to the liver (portal hypertension). It uses a special ultrasound with contrast to learn more about the condition.
This trial tests if the drug carvedilol can prevent liver-related emergencies or death in people with cirrhosis and high blood pressure in the liver. It may help those who are stable right now but at risk for a sudden worsening.
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