Stopping beta blocker in controlled cirrhosis
Part of Digestive system clinical trials.
This study is checking if it is safe for people with cirrhosis (liver scarring) to stop taking a certain blood pressure medicine (non-selective beta blockers) if their main liver problem is under control. If you've had varices or bleeding in the past and your liver is now stable, this trial will see if you can safely stop the medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have been diagnosed with cirrhosis (scarring of the liver).
- You have or had varices (enlarged veins) or bleeding in your esophagus/stomach, and you were prescribed a non-selective beta blocker medicine for it.
- The main cause of your cirrhosis (hepatitis B, hepatitis C, or alcohol) is well managed (virus suppressed or you've been abstinent from alcohol for a long time).
- Your liver stiffness measurement (a type of scan) is less than 25 kPa (a measure of liver scarring).
- You have not had serious liver complications in the past year (like jaundice, fluid in the belly, or confusion).
- You do not have liver cancer, a blood clot in the liver's main vein, or any other cancer that has not been cured for over 5 years.
- You have not had a liver transplant or liver surgery.
- You are not taking a non-selective beta blocker for other reasons (like heart problems or high blood pressure).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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