Baricitinib for active cardiac sarcoidosis
Treatments studied
Part of Blood & lymphatic, Immune system & allergy clinical trials.
This trial tests a medication called baricitinib (a JAK inhibitor) for people with active cardiac sarcoidosis. It may help reduce inflammation in the heart and improve heart function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with cardiac sarcoidosis (heart sarcoidosis) and have a heart PET scan showing active inflammation within the last 6 weeks.
- You are not currently taking strong immunosuppressants like biologics or other JAK inhibitors, or you are on low-dose prednisone (≤20 mg daily) or a steroid-sparing drug like methotrexate.
- You have not had a blood clot (DVT or pulmonary embolism) and are not at high risk for one.
- You do not currently smoke cigarettes.
- Your kidney function is good (estimated GFR ≥30) and your blood counts and liver tests are within safe limits.
- You do not have an active infection or recent cancer (except certain treated skin or cervical cancers).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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