Baricitinib for heart inflammation from sarcoidosis
Treatments studied
Part of Blood & lymphatic, Immune system & allergy clinical trials.
This trial tests a pill called baricitinib to see if it can reduce inflammation in the heart caused by sarcoidosis. The goal is to help control the disease and improve heart function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of cardiac sarcoidosis, either from a biopsy or based on symptoms like unexplained heart rhythm problems or low heart pumping function.
- A PET scan within the last 6 weeks must show active inflammation in your heart.
- You may be on low-dose steroids (up to 20 mg daily) or certain steroid-sparing drugs, but not other stronger immunosuppressants.
- You must not have had certain biologic treatments (like rituximab or infliximab) in the last 6 months.
- You must not have a history of blood clots or be at high risk for them, and you must not currently smoke.
- Your kidney and liver function must be within acceptable limits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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