Minimally invasive clot removal with tenecteplase for deep brain bleed
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests a minimally invasive procedure to remove deep brain bleeds using a special puncture guided by brain imaging, combined with a clot-dissolving drug called tenecteplase. It may help reduce damage from the bleed and improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 79 years old.
- You had a spontaneous deep brain bleed (in the basal ganglia or thalamus) that is 20 to 50 mL in size.
- Your symptoms started within 24 hours of your first CT scan.
- A follow-up CT scan at least 6 hours later shows the bleed has stopped growing (less than 5 mL increase).
- You have a Glasgow Coma Scale score between 5 and 14 (meaning you are not fully awake but respond to some stimulation).
- You are not taking blood thinners (like warfarin, apixaban, or clopidogrel) and do not have a bleeding disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a minimally invasive procedure using a special clot-busting medicine (tenecteplase) for a certain type of brain bleed. It aims to see if this approach improves recovery compared to standard care.
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This trial tests a minimally invasive surgery to remove blood clots deep in the brain after a spontaneous bleed. It may help patients with moderate to large bleeds who are at least 18 and up to 80 years old.
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