Intraventricular clot removal with medication after brain bleed
Part of Blood & lymphatic, Brain & nervous system clinical trials.
This trial tests a clot-busting drug (rhTNK-tPA) to remove blood from the ventricles (fluid spaces deep in the brain) after a spontaneous brain bleed. It may help patients whose ventricles are blocked by a large clot, reducing pressure and improving recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You had a sudden brain bleed within the last 24 hours before your first CT scan.
- The bleed is spontaneous (not caused by a tumor, aneurysm, or other known cause).
- The clot in the fluid spaces of your brain is larger than 20 milliliters and is blocking the flow of fluid.
- You have a drain placed in the fluid space of your brain (external ventricular drain) before joining the study.
- Your blood pressure is stable (below 180 mmHg) for at least 6 hours before enrollment.
- You have not taken blood thinners (like warfarin, dabigatran, rivaroxaban, or clopidogrel) in the past week (aspirin is okay).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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