Nasal spray for recent concussion
Part of Brain & nervous system, Injuries & trauma clinical trials.
This study tests an experimental nasal spray called ONP-002 for people with a recent mild concussion. It looks at safety and how well the body handles the drug, with a focus on helping recovery after a head injury.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 55 years old.
- You have been diagnosed with a mild concussion and had a CT scan that showed no bleeding.
- You can get the first dose of the study drug within 12 hours of your injury.
- You do not have a nosebleed or a blocked nasal passage.
- You are willing to use birth control or not become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a Medrol “dose pack” (a short course of steroid medicine taken by mouth) can reduce acute headache pain after a concussion. It may help people whose concussion headaches are frequent and severe soon after injury.
This trial tests whether a steroid called methylprednisolone, given early after a head injury, helps reduce brain swelling and improve recovery. It is for people with moderate to severe traumatic brain injury who can start treatment within 12 hours.
This study follows people who receive intranasal stem cell or exosome therapy (tiny packages from special cells) for brain or neurological conditions like stroke, brain injury, or cerebral palsy. Researchers track how well the treatment works by measuring inflammation markers in the blood and monitoring clinical improvements over time.
This study tests a practical rehabilitation approach for people with a recent mild concussion (mTBI). You may be able to join if your injury happened recently and your symptoms match a “mild” concussion pattern on your medical record.
This trial tests whether steroids can help reduce brain swelling in people with mild to moderate traumatic brain injury. It is for patients who have a bruise on the brain seen on a CT scan and signs of increased pressure in the head.
This study tests if a combination of two nasal sprays (a decongestant and a steroid) can help people with chronic nasal blockage who haven't gotten relief from steroid sprays alone.
Hear when a new Mild Traumatic Brain Injury, Concussion trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.