Isatuximab for multiple myeloma with 1q21 abnormality
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests if adding the drug isatuximab to standard treatments helps people whose multiple myeloma has returned or stopped responding, especially if their cancer cells have an extra copy of a certain gene (1q21). The study checks how well these drugs work together.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older
- You have multiple myeloma that came back or did not respond to at least one prior treatment, including isatuximab
- Doctors have checked your cancer cells for a genetic change called 1q21, either when you were first diagnosed or when it came back
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This early-phase study tests isatuximab (an anti-cancer antibody) combined with other study medicines in people whose multiple myeloma has come back or not responded. It aims to improve control of the disease after you’ve already had multiple prior treatments.
This trial tests a new drug called QI-019A for people whose multiple myeloma has returned or stopped responding to at least two prior treatments. The goal is to see if it is safe and if it can help control the disease.
This trial tests a combination of two drugs—elranatamab and isatuximab—for people with multiple myeloma that has come back or stopped responding to at least two prior treatments. The goal is to see if this new combination can help control the disease.
This trial tests a combination of two drugs, CM336 and Isatuximab, for people newly diagnosed with multiple myeloma that has caused kidney damage. The goal is to see if this treatment can help control the myeloma while also addressing the kidney issues.
This trial tests a combination of drugs (isatuximab, bortezomib, lenalidomide, and dexamethasone) for people with newly diagnosed high-risk multiple myeloma who cannot or choose not to have a stem cell transplant. It aims to see if this treatment helps control the disease better.
This trial tests a combination of four drugs—isatuximab, bortezomib, lenalidomide, and dexamethasone—for people with newly diagnosed multiple myeloma who cannot have a stem cell transplant. The goal is to see if adding isatuximab helps control the cancer better.
Hear when a new Multiple Mieloma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.